Shear wave elastography in diffuse thyroid disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73608908" target="_blank" >RIV/61989592:15110/21:73608908 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/21:N0000031

Výsledek na webu

<a href="https://biomed.papers.upol.cz/pdfs/bio/2021/02/06.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2021/02/06.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2020.018" target="_blank" >10.5507/bp.2020.018</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Shear wave elastography in diffuse thyroid disease

Popis výsledku v původním jazyce

Aim. Our aim was to examine the contribution of shear wave elastography to ultrasonographic assessment in diffuse thyroid disease, specifically to evaluate the stiffness of the thyroid gland in diffuse thyroid disease and compare it with healthy controls. Methods. A total of 46 patients with diffuse thyroid disease were examined clinically, by conventional ultrasound, and shear wave elastography. The conventional ultrasound parameters followed were: volume, margin quality, presence of nodules, and vascularisation. We measured the mean, minimum, and maximum stiffnesses by shear wave elastography. Results were correlated with values in 128 healthy subjects. Results. Patients with diffuse thyroid disease had significantly higher mean and maximal stiffnesses of the thyroid gland: 12.5 +/- 5 kPa and 35.3 +/- 12.8 kPa, respectively, and lower minimal stiffness: 0.5 +/- 0.6 kPa than the healthy control group with mean, maximal, and minimal values of 9.5 +/- 3.6 kPa, 22.5 +/- 7.3 kPa, and 2.2 +/- 2.1 kPa (P&lt;0.001). Stiffness values were positively correlated with BMI and volume of the thyroid; they did not correlate with margin quality, presence of nodules nor vascularisation. Compared with healthy volunteers, thyroid glands of patients with diffuse thyroid disease had a blurred margin more frequently and the amount of nodules and vascularisation were higher. Patients with Graves-Basedow disease did not have significantly different mean, maximal, nor minimal stiffnesses than those with thyroiditis. Conclusion. Both mean and maximal stiffness of the thyroid gland are significantly higher in diffuse thyroid disease than in the healthy population, while minimal stiffness is lower.

Název v anglickém jazyce

Shear wave elastography in diffuse thyroid disease

Popis výsledku anglicky

Aim. Our aim was to examine the contribution of shear wave elastography to ultrasonographic assessment in diffuse thyroid disease, specifically to evaluate the stiffness of the thyroid gland in diffuse thyroid disease and compare it with healthy controls. Methods. A total of 46 patients with diffuse thyroid disease were examined clinically, by conventional ultrasound, and shear wave elastography. The conventional ultrasound parameters followed were: volume, margin quality, presence of nodules, and vascularisation. We measured the mean, minimum, and maximum stiffnesses by shear wave elastography. Results were correlated with values in 128 healthy subjects. Results. Patients with diffuse thyroid disease had significantly higher mean and maximal stiffnesses of the thyroid gland: 12.5 +/- 5 kPa and 35.3 +/- 12.8 kPa, respectively, and lower minimal stiffness: 0.5 +/- 0.6 kPa than the healthy control group with mean, maximal, and minimal values of 9.5 +/- 3.6 kPa, 22.5 +/- 7.3 kPa, and 2.2 +/- 2.1 kPa (P&lt;0.001). Stiffness values were positively correlated with BMI and volume of the thyroid; they did not correlate with margin quality, presence of nodules nor vascularisation. Compared with healthy volunteers, thyroid glands of patients with diffuse thyroid disease had a blurred margin more frequently and the amount of nodules and vascularisation were higher. Patients with Graves-Basedow disease did not have significantly different mean, maximal, nor minimal stiffnesses than those with thyroiditis. Conclusion. Both mean and maximal stiffness of the thyroid gland are significantly higher in diffuse thyroid disease than in the healthy population, while minimal stiffness is lower.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

<a href="/cs/project/NV16-31881A" target="_blank" >NV16-31881A: Technické aspekty a klinické aplikace ultrasonografické elastografie v oblasti hlavy a krku</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS-OLOMOUC

ISSN

1213-8118

e-ISSN

—

Svazek periodika

165

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

152-156

Kód UT WoS článku

000660244900006

EID výsledku v databázi Scopus

2-s2.0-85108804463