Morphometric analysis of Hofbauer cells in normal placenta and chorioamnionitis in humans

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73611240" target="_blank" >RIV/61989592:15110/21:73611240 - isvavai.cz</a>

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/full/10.1111/ahe.12644" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1111/ahe.12644</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/ahe.12644" target="_blank" >10.1111/ahe.12644</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Morphometric analysis of Hofbauer cells in normal placenta and chorioamnionitis in humans

Popis výsledku v původním jazyce

Hofbauer cells are macrophages residing in the stroma of placental villi and play a number of roles during normal pregnancy, as well as pathological conditions. A comparative morphometric analysis of Hofbauer cells, in particular to investigate the number of cells, their size and shape in samples of normal placenta from 1st trimester and term and with chorioamnionitis was performed. Tissue samples were immunostained for CD206 antigen and evaluated using ImageJ software. We detected significant changes in number and morphology of HBCs between normal placenta and placenta with chorioamnionitis samples. In chorioamnionitis, the cells were unevenly distributed within the villi, generally present in higher numbers, larger and more elongated than those in normal 1st trimester and term placenta. We could speculate that changed morphology of HBCs in chorioamnionitis can be associated with an alteration in their anti-inflammatory function.

Název v anglickém jazyce

Morphometric analysis of Hofbauer cells in normal placenta and chorioamnionitis in humans

Popis výsledku anglicky

Hofbauer cells are macrophages residing in the stroma of placental villi and play a number of roles during normal pregnancy, as well as pathological conditions. A comparative morphometric analysis of Hofbauer cells, in particular to investigate the number of cells, their size and shape in samples of normal placenta from 1st trimester and term and with chorioamnionitis was performed. Tissue samples were immunostained for CD206 antigen and evaluated using ImageJ software. We detected significant changes in number and morphology of HBCs between normal placenta and placenta with chorioamnionitis samples. In chorioamnionitis, the cells were unevenly distributed within the villi, generally present in higher numbers, larger and more elongated than those in normal 1st trimester and term placenta. We could speculate that changed morphology of HBCs in chorioamnionitis can be associated with an alteration in their anti-inflammatory function.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10601 - Cell biology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ANATOMIA HISTOLOGIA EMBRYOLOGIA

ISSN

0340-2096

e-ISSN

—

Svazek periodika

50

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

8

Strana od-do

396-403

Kód UT WoS článku

000597846100001

EID výsledku v databázi Scopus

2-s2.0-85097394250