Temperature sensation in Parkinson's disease measured by quantitative sensory testing: a single-center, case-control study.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F23%3A73609506" target="_blank" >RIV/61989592:15110/23:73609506 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/23:10157893

Výsledek na webu

<a href="https://www.tandfonline.com/doi/full/10.1080/00207454.2021.1991922" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/00207454.2021.1991922</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/00207454.2021.1991922" target="_blank" >10.1080/00207454.2021.1991922</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Temperature sensation in Parkinson's disease measured by quantitative sensory testing: a single-center, case-control study.

Popis výsledku v původním jazyce

Background The pathophysiology of abnormal temperature sensation in Parkinson&apos;s disease (PD) remains unclear. Abnormal thermal detection does not seem to depend on the dopaminergic deficit, suggesting that other systems play a role in these changes, probably both central and peripheral. Methods We measured thermal detection thresholds (TDT) using quantitative sensory testing (QST) in 28 patients with PD and compared them with 15 healthy controls. Results Of 28 patients, 21% had increased TDT according to the normative data. TDT were higher on the dominant side. No correlation between TDT and disease duration, severity of motor impairment, and dopaminergic therapy was observed. 50% of the patients had difficulty differentiating between warm and cold stimuli, as TDT were within the normal range in most of these patients. Conclusions Twenty-one percent of the patients in our study had increased TDT according to the normative data. Abnormal thermal detection was more pronounced on the dominant side. Abnormal differentiation between the thermal stimuli suggest impaired central processing of thermal information

Název v anglickém jazyce

Temperature sensation in Parkinson's disease measured by quantitative sensory testing: a single-center, case-control study.

Popis výsledku anglicky

Background The pathophysiology of abnormal temperature sensation in Parkinson&apos;s disease (PD) remains unclear. Abnormal thermal detection does not seem to depend on the dopaminergic deficit, suggesting that other systems play a role in these changes, probably both central and peripheral. Methods We measured thermal detection thresholds (TDT) using quantitative sensory testing (QST) in 28 patients with PD and compared them with 15 healthy controls. Results Of 28 patients, 21% had increased TDT according to the normative data. TDT were higher on the dominant side. No correlation between TDT and disease duration, severity of motor impairment, and dopaminergic therapy was observed. 50% of the patients had difficulty differentiating between warm and cold stimuli, as TDT were within the normal range in most of these patients. Conclusions Twenty-one percent of the patients in our study had increased TDT according to the normative data. Abnormal thermal detection was more pronounced on the dominant side. Abnormal differentiation between the thermal stimuli suggest impaired central processing of thermal information

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

<a href="/cs/project/EF16_019%2F0000868" target="_blank" >EF16_019/0000868: Molekulární, buněčný a klinický přístup ke zdravému stárnutí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Neuroscience

ISSN

0020-7454

e-ISSN

1563-5279

Svazek periodika

133

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

834-839

Kód UT WoS článku

000712346300001

EID výsledku v databázi Scopus

2-s2.0-85118300924