Hypertension, hyperlipidaemia and thrombophilia as the most common risk factors for retinal vein occlusion in patients under 50 years

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F24%3A73616238" target="_blank" >RIV/61989592:15110/24:73616238 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/24:10446976 RIV/00098892:_____/24:10157569

Výsledek na webu

<a href="https://biomed.papers.upol.cz/getrevsrc.php?identification=public&mag=bio&raid=3261&type=fin&ver=2" target="_blank" >https://biomed.papers.upol.cz/getrevsrc.php?identification=public&mag=bio&raid=3261&type=fin&ver=2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2022.036" target="_blank" >10.5507/bp.2022.036</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hypertension, hyperlipidaemia and thrombophilia as the most common risk factors for retinal vein occlusion in patients under 50 years

Popis výsledku v původním jazyce

Background and Aims. Cardiovascular (CV) diseases are the most common risk factors (RFs) for retinal vein occlusion (RVO) development in general. The aim of this study was to identify the most frequent causes of RVO in patientsunder 50.Methods. We retrospectively evaluated a group of patients with RVO under 50 years. The parameters of interest included age and sex, RVO type, presence of arterial hypertension (HT), hyperlipidaemia (HLD), diabetes mellitus (DM),congenital thrombophilic disorder (TD), obstructive sleep apnoea syndrome (OSAS), thyroid eye disease (TED), use ofhormone contraception (HC) or hormone replacement therapy (HRT), glaucoma and other potential RFs. Patients withcentral RVO (CRVO), hemi-central RVO (HRVO), branch RVO (BRVO), impending CRVO and combined arterial-venous(AV) occlusion were included.Results. The group consisted of 110 eyes of 103 patients. CV disease was the most common systemic abnormality.55.3% patients had HT, 17.5% had HLD. TD was the third most frequent RF (12.6%). The cohort also included patientswith DM (6.8%), glaucoma (6.8%) and women using HC/HRT (26.2% of female patients). There were isolated cases ofRVO due to retinal vasculitis, intense exercise, antiphospholipid syndrome and COVID-19 pneumonia. None of thepatients had OSAS, TED or a haemato-oncological disease. The etiology remained unexplained in 20.4% patients. Nodifference was observed in RF occurrence between patients with CRVO and HRVO and those with BRVO.Conclusion. The most common systemic abnormality in our cohort was CV disease, especially HT and HLD. The riskfactors for central, hemi-central and branch RVOs were similar.

Název v anglickém jazyce

Hypertension, hyperlipidaemia and thrombophilia as the most common risk factors for retinal vein occlusion in patients under 50 years

Popis výsledku anglicky

Background and Aims. Cardiovascular (CV) diseases are the most common risk factors (RFs) for retinal vein occlusion (RVO) development in general. The aim of this study was to identify the most frequent causes of RVO in patientsunder 50.Methods. We retrospectively evaluated a group of patients with RVO under 50 years. The parameters of interest included age and sex, RVO type, presence of arterial hypertension (HT), hyperlipidaemia (HLD), diabetes mellitus (DM),congenital thrombophilic disorder (TD), obstructive sleep apnoea syndrome (OSAS), thyroid eye disease (TED), use ofhormone contraception (HC) or hormone replacement therapy (HRT), glaucoma and other potential RFs. Patients withcentral RVO (CRVO), hemi-central RVO (HRVO), branch RVO (BRVO), impending CRVO and combined arterial-venous(AV) occlusion were included.Results. The group consisted of 110 eyes of 103 patients. CV disease was the most common systemic abnormality.55.3% patients had HT, 17.5% had HLD. TD was the third most frequent RF (12.6%). The cohort also included patientswith DM (6.8%), glaucoma (6.8%) and women using HC/HRT (26.2% of female patients). There were isolated cases ofRVO due to retinal vasculitis, intense exercise, antiphospholipid syndrome and COVID-19 pneumonia. None of thepatients had OSAS, TED or a haemato-oncological disease. The etiology remained unexplained in 20.4% patients. Nodifference was observed in RF occurrence between patients with CRVO and HRVO and those with BRVO.Conclusion. The most common systemic abnormality in our cohort was CV disease, especially HT and HLD. The riskfactors for central, hemi-central and branch RVOs were similar.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

<a href="/cs/project/NU21J-01-00017" target="_blank" >NU21J-01-00017: Včasná detekce rozvoje endokrinní orbitopatie u pacientů s dysfunkcí štítné žlázy a metody hodnocení její aktivity a závažnosti</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS-OLOMOUC

ISSN

1213-8118

e-ISSN

1804-7521

Svazek periodika

168

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

44-49

Kód UT WoS článku

000849745500001

EID výsledku v databázi Scopus

2-s2.0-85187724620