Multicomponent Reactions: A Promising Approach to Isotope Labeling
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F24%3A73627288" target="_blank" >RIV/61989592:15110/24:73627288 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989592:15640/24:73627288
Výsledek na webu
<a href="https://www.thieme-connect.de/products/ejournals/html/10.1055/a-2331-6399" target="_blank" >https://www.thieme-connect.de/products/ejournals/html/10.1055/a-2331-6399</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/a-2331-6399" target="_blank" >10.1055/a-2331-6399</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Multicomponent Reactions: A Promising Approach to Isotope Labeling
Popis výsledku v původním jazyce
Isotopic labeling is an attractive modality that has been widely used in many aspects of chemistry, the life sciences, and medical research; especially deuterated drugs and radioactive molecules have been used in the diagnosis and treatment of cancer and neurodegenerative diseases. The widespread application and rapid development of isotopically labeled molecules has led to an increased demand for new isotopic labeling chemical methods to synthesize highly specific molecules bearing defined nuclides. Multicomponent reactions (MCRs) are modular build-up approaches for the rapid generation of complex molecules often containing biologically relevant scaffold structures. There is great potential to use MCRs to construct isotopically labeled molecules because assembly speed and reaction diversity are key advantages of MCR. In this review, we provide an overview of the recent literature on this topic that can provide insight into the application of MCRs in the field of isotopic labeling.
Název v anglickém jazyce
Multicomponent Reactions: A Promising Approach to Isotope Labeling
Popis výsledku anglicky
Isotopic labeling is an attractive modality that has been widely used in many aspects of chemistry, the life sciences, and medical research; especially deuterated drugs and radioactive molecules have been used in the diagnosis and treatment of cancer and neurodegenerative diseases. The widespread application and rapid development of isotopically labeled molecules has led to an increased demand for new isotopic labeling chemical methods to synthesize highly specific molecules bearing defined nuclides. Multicomponent reactions (MCRs) are modular build-up approaches for the rapid generation of complex molecules often containing biologically relevant scaffold structures. There is great potential to use MCRs to construct isotopically labeled molecules because assembly speed and reaction diversity are key advantages of MCR. In this review, we provide an overview of the recent literature on this topic that can provide insight into the application of MCRs in the field of isotopic labeling.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10401 - Organic chemistry
Návaznosti výsledku
Projekt
<a href="/cs/project/LX22NPO5102" target="_blank" >LX22NPO5102: Národní ústav pro výzkum rakoviny</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2024
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
SYNLETT
ISSN
0936-5214
e-ISSN
1437-2096
Svazek periodika
35
Číslo periodika v rámci svazku
19
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
17
Strana od-do
2174-2190
Kód UT WoS článku
001315382800003
EID výsledku v databázi Scopus
2-s2.0-85204740847