Predictors of good clinical outcome in patients with acute stroke undergoing endovascular treatment – results from CERBERUS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15120%2F17%3A73583150" target="_blank" >RIV/61989592:15120/17:73583150 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/17:10367760 RIV/00216208:11140/17:10367760 RIV/00216208:11150/17:10367760 RIV/00179906:_____/17:10367760 a 4 dalších

Výsledek na webu

<a href="http://dx.doi.org/10.14735/amcsnn2017666" target="_blank" >http://dx.doi.org/10.14735/amcsnn2017666</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14735/amcsnn2017666" target="_blank" >10.14735/amcsnn2017666</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Predictors of good clinical outcome in patients with acute stroke undergoing endovascular treatment – results from CERBERUS

Popis výsledku v původním jazyce

Background: Endovascular therapy (EVT) with stent retrievers has been shown to be superior and safe (in the anterior circulation) in comparison to intravenous thrombolysis (IVT) alone or no specific therapy. We compared clinical outcome between patients undergoing EVT admitted directly to comprehensive stroke centers (CSCs) and patients transfer red from primary stroke centers (PSCs) to a CSC. Materials and methods: Demographics, risk factors, and medical history of all consecutive EVT-treated stroke patients in col laborating stroke centers were collected. Patients were divided into three groups: treatment with IVT in a PSC before transfer to a CSC for EVT; treatment with IVT directly in a CSC with subsequent EVT in the same center; no treatment with IVT before EVT. Neurological status using the National Institutes of Health Stroke Scale (NIHSS) on admission and at day 7 and self-sufficiency using the modified Rankin Scale (mRS) at day 90 were assessed. Favorable clinical outcome was defined as an mRS score of 0– 2. Follow-up computed tomography or magnetic resonance imaging was done to determine symptomatic intracerebral hemorrhage (SICH). Results: A total of 568 patients (313 males; mean age, 66.1 ± 13.2 years) were registered from January 2006 to the end of July 2015. Patients in all three groups did not differ in baseline characteristics except for the time to the start of EVT. The average delay of EVT start in patients transfer red from PSC to CSC was 45 min. Subgroups did not differ significantly in SICH prevalence (over all prevalence 5.5%) and favorable clinical outcome (over all 46.7%). Conclusion: The benefit of direct transfer to a CSC merits further investigation. The present study showed that both approaches to stroke patient transport organization in the Czech Republic are comparably efficient and safe.

Název v anglickém jazyce

Predictors of good clinical outcome in patients with acute stroke undergoing endovascular treatment – results from CERBERUS

Popis výsledku anglicky

Background: Endovascular therapy (EVT) with stent retrievers has been shown to be superior and safe (in the anterior circulation) in comparison to intravenous thrombolysis (IVT) alone or no specific therapy. We compared clinical outcome between patients undergoing EVT admitted directly to comprehensive stroke centers (CSCs) and patients transfer red from primary stroke centers (PSCs) to a CSC. Materials and methods: Demographics, risk factors, and medical history of all consecutive EVT-treated stroke patients in col laborating stroke centers were collected. Patients were divided into three groups: treatment with IVT in a PSC before transfer to a CSC for EVT; treatment with IVT directly in a CSC with subsequent EVT in the same center; no treatment with IVT before EVT. Neurological status using the National Institutes of Health Stroke Scale (NIHSS) on admission and at day 7 and self-sufficiency using the modified Rankin Scale (mRS) at day 90 were assessed. Favorable clinical outcome was defined as an mRS score of 0– 2. Follow-up computed tomography or magnetic resonance imaging was done to determine symptomatic intracerebral hemorrhage (SICH). Results: A total of 568 patients (313 males; mean age, 66.1 ± 13.2 years) were registered from January 2006 to the end of July 2015. Patients in all three groups did not differ in baseline characteristics except for the time to the start of EVT. The average delay of EVT start in patients transfer red from PSC to CSC was 45 min. Subgroups did not differ significantly in SICH prevalence (over all prevalence 5.5%) and favorable clinical outcome (over all 46.7%). Conclusion: The benefit of direct transfer to a CSC merits further investigation. The present study showed that both approaches to stroke patient transport organization in the Czech Republic are comparably efficient and safe.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a slovenská neurologie a neurochirurgie

ISSN

1210-7859

e-ISSN

—

Svazek periodika

80

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

666-674

Kód UT WoS článku

000417541400005

EID výsledku v databázi Scopus

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