The relationship between atherosclerosis and dementia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15120%2F24%3A73626451" target="_blank" >RIV/61989592:15120/24:73626451 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/24:A250380C RIV/00216208:11150/24:10481546 RIV/00179906:_____/24:10481546 RIV/00843989:_____/24:E0111061 RIV/61989592:15110/24:73626451

Výsledek na webu

<a href="https://cejph.szu.cz/artkey/cjp-202401-0001_the-relationship-between-atherosclerosis-and-dementia.php" target="_blank" >https://cejph.szu.cz/artkey/cjp-202401-0001_the-relationship-between-atherosclerosis-and-dementia.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21101/cejph.a7848" target="_blank" >10.21101/cejph.a7848</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The relationship between atherosclerosis and dementia

Popis výsledku v původním jazyce

SUMMARYObjective: The main objective is to confirm a hypothesis that atherosclerosis, through various mechanisms, considerably influences cognitiveimpairment and significantly increases the risk for developing dementia. Complete sample should be 920 individuals. The present study aimed toanalyse epidemiological data from a questionnaire survey.Methods: The work was carried out in the form of an epidemiological case control study. Subjects are enrolled in the study based on resultsof the following examinations carried out in neurology departments and outpatient centres during the project NU20-09-00119 from 2020 to 2023.Respondents were divided into four research groups according to the results of clinical examination for the presence of atherosclerosis anddementia. The survey was mainly concerned with risk factors for both atherosclerosis and dementia. It contained questions on lifestyle factors,cardiovascular risk factors, leisure activities, and hobbies.Results: Analysis of the as yet incomplete sample of 877 subjects has yielded the following selected results: on average, 16% of subjects withoutdementia had primary education while the proportion was 45.2% in the group with both dementia and atherosclerosis. Subjects with dementiadid mainly physical work. Low physical activity was more frequently noted in dementia groups (Group 2 – 54.4% and Group 3 – 47.2%) than insubjects without dementia (Group 1 – 19.6% and Group 4 – 25.8%). Coronary heart disease was more frequently reported by dementia patients(33.95%) than those without dementia (16.05%).Conclusion: Cognitively impaired individuals, in particular those with vascular cognitive impairment, have poorer quality of life and shortersurvival. Risk factors contributing to such impairment are similar to those for ischaemic or haemorrhagic stroke. It may be concluded that most ofthe analysed risk factors play a role in the development of both atherosclerosis and dementia.

Název v anglickém jazyce

The relationship between atherosclerosis and dementia

Popis výsledku anglicky

SUMMARYObjective: The main objective is to confirm a hypothesis that atherosclerosis, through various mechanisms, considerably influences cognitiveimpairment and significantly increases the risk for developing dementia. Complete sample should be 920 individuals. The present study aimed toanalyse epidemiological data from a questionnaire survey.Methods: The work was carried out in the form of an epidemiological case control study. Subjects are enrolled in the study based on resultsof the following examinations carried out in neurology departments and outpatient centres during the project NU20-09-00119 from 2020 to 2023.Respondents were divided into four research groups according to the results of clinical examination for the presence of atherosclerosis anddementia. The survey was mainly concerned with risk factors for both atherosclerosis and dementia. It contained questions on lifestyle factors,cardiovascular risk factors, leisure activities, and hobbies.Results: Analysis of the as yet incomplete sample of 877 subjects has yielded the following selected results: on average, 16% of subjects withoutdementia had primary education while the proportion was 45.2% in the group with both dementia and atherosclerosis. Subjects with dementiadid mainly physical work. Low physical activity was more frequently noted in dementia groups (Group 2 – 54.4% and Group 3 – 47.2%) than insubjects without dementia (Group 1 – 19.6% and Group 4 – 25.8%). Coronary heart disease was more frequently reported by dementia patients(33.95%) than those without dementia (16.05%).Conclusion: Cognitively impaired individuals, in particular those with vascular cognitive impairment, have poorer quality of life and shortersurvival. Risk factors contributing to such impairment are similar to those for ischaemic or haemorrhagic stroke. It may be concluded that most ofthe analysed risk factors play a role in the development of both atherosclerosis and dementia.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30302 - Epidemiology

Projekt

<a href="/cs/project/NU20-09-00119" target="_blank" >NU20-09-00119: Možný vliv aterosklerózy na rozvoj demence</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Central European Journal of Public Health

ISSN

1210-7778

e-ISSN

1803-1048

Svazek periodika

32

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

9-15

Kód UT WoS článku

001234975200010

EID výsledku v databázi Scopus

2-s2.0-85191623093