Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15120%2F24%3A73626472" target="_blank" >RIV/61989592:15120/24:73626472 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/23:A2502NEK RIV/61989592:15110/24:73626472

Výsledek na webu

<a href="https://otolaryngologypl.com/article/536158/en" target="_blank" >https://otolaryngologypl.com/article/536158/en</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5604/01.3001.0053.6158" target="_blank" >10.5604/01.3001.0053.6158</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review

Popis výsledku v původním jazyce

Introduction: The early detection and diagnosis of dementia are of key importance in treatment, slowing disease progression,or suppressing symptoms. The possible role of changes in the sense of smell is considered with regard to potential markers forearly detection of Alzheimer’s disease (AD).Materials and methods: A literature search was conducted using the electronic databases PubMed, Scopus, and Web of Sciencebetween May 30, 2022 and August 2, 2022. The term “dementia” was searched with keyword combinations related to olfaction.Results: A total of 1,288 records were identified through the database search. Of these articles, 49 were ultimately included inthe analysis. The results showed the potential role of changes in the sense of smell as potential biomarkers for early detectionof AD. Multiple studies have shown that olfactory impairment may be observed in patients with AD, PD, MCI, or other typesof dementia. Even though smell tests are able to detect olfactory loss caused by neurodegenerative diseases, they cannotreliably distinguish between certain diseases.Conclusions: In individuals with cognitive impairment or neurodegenerative diseases, olfactory assessment has repeatedlybeen reported to be used for early diagnosis, but not for differential diagnosis.

Název v anglickém jazyce

Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review

Popis výsledku anglicky

Introduction: The early detection and diagnosis of dementia are of key importance in treatment, slowing disease progression,or suppressing symptoms. The possible role of changes in the sense of smell is considered with regard to potential markers forearly detection of Alzheimer’s disease (AD).Materials and methods: A literature search was conducted using the electronic databases PubMed, Scopus, and Web of Sciencebetween May 30, 2022 and August 2, 2022. The term “dementia” was searched with keyword combinations related to olfaction.Results: A total of 1,288 records were identified through the database search. Of these articles, 49 were ultimately included inthe analysis. The results showed the potential role of changes in the sense of smell as potential biomarkers for early detectionof AD. Multiple studies have shown that olfactory impairment may be observed in patients with AD, PD, MCI, or other typesof dementia. Even though smell tests are able to detect olfactory loss caused by neurodegenerative diseases, they cannotreliably distinguish between certain diseases.Conclusions: In individuals with cognitive impairment or neurodegenerative diseases, olfactory assessment has repeatedlybeen reported to be used for early diagnosis, but not for differential diagnosis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30302 - Epidemiology

Projekt

<a href="/cs/project/NU20-09-00119" target="_blank" >NU20-09-00119: Možný vliv aterosklerózy na rozvoj demence</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polish Journal of Otolaryngology

ISSN

0030-6657

e-ISSN

2300-8423

Svazek periodika

78

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

17

Strana od-do

1-17

Kód UT WoS článku

001275286600001

EID výsledku v databázi Scopus

2-s2.0-85190788185