Influence of Disease Severity on Fatigue in Patients with Parkinson's Disease Is Mainly Mediated by Symptoms of Depression

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15260%2F13%3A33147227" target="_blank" >RIV/61989592:15260/13:33147227 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1159/000351779" target="_blank" >http://dx.doi.org/10.1159/000351779</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000351779" target="_blank" >10.1159/000351779</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Influence of Disease Severity on Fatigue in Patients with Parkinson's Disease Is Mainly Mediated by Symptoms of Depression

Popis výsledku v původním jazyce

Purpose: Fatigue is a frequent non-motor complaint of patients with Parkinson's disease (PD). Despite increasing knowledge on fatigue, the factors leading to its development are still not recognised. The aim of this investigation was to test, using structural equation modelling, the hypothesis that the influence of disease severity on fatigue is mediated by symptoms of depression in patients with PD. Method: The sample consisted of 190 PD patients (93 men, 48.9%, mean age 68.2 +/- 9.3 years, mean disease duration 6.4 +/- 4.7 years) recruited from hospitals and outpatient clinics in the East Slovakia region. The Multidimensional Fatigue Inventory, the Hospital Anxiety and Depression Scale and the Unified Parkinson's Disease Rating Scale were used. LISREL was used to analyse the data. Results: Disease severity was directly associated with symptoms of depression (beta = 0.26) and directly affected fatigue in terms of increased levels of general fatigue (beta = 0.35), physical fatigue (bet

Název v anglickém jazyce

Influence of Disease Severity on Fatigue in Patients with Parkinson's Disease Is Mainly Mediated by Symptoms of Depression

Popis výsledku anglicky

Purpose: Fatigue is a frequent non-motor complaint of patients with Parkinson's disease (PD). Despite increasing knowledge on fatigue, the factors leading to its development are still not recognised. The aim of this investigation was to test, using structural equation modelling, the hypothesis that the influence of disease severity on fatigue is mediated by symptoms of depression in patients with PD. Method: The sample consisted of 190 PD patients (93 men, 48.9%, mean age 68.2 +/- 9.3 years, mean disease duration 6.4 +/- 4.7 years) recruited from hospitals and outpatient clinics in the East Slovakia region. The Multidimensional Fatigue Inventory, the Hospital Anxiety and Depression Scale and the Unified Parkinson's Disease Rating Scale were used. LISREL was used to analyse the data. Results: Disease severity was directly associated with symptoms of depression (beta = 0.26) and directly affected fatigue in terms of increased levels of general fatigue (beta = 0.35), physical fatigue (bet

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FQ - Veřejné zdravotnictví, sociální lékařství

OECD FORD obor

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Projekt

<a href="/cs/project/EE.2.3.20.0063" target="_blank" >EE.2.3.20.0063: Sociální determinanty zdraví u sociálně a zdravotně znevýhodněných a jiných skupin populace</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European neurology

ISSN

0014-3022

e-ISSN

—

Svazek periodika

70

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

9

Strana od-do

201-209

Kód UT WoS článku

000326135500017

EID výsledku v databázi Scopus

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