Biological redox activity: Its importance, methods for its quantification and implication for health and disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F00%3A00000991" target="_blank" >RIV/61989592:15310/00:00000991 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Biological redox activity: Its importance, methods for its quantification and implication for health and disease

Popis výsledku v původním jazyce

Cellular redox phenomena are involved in numerous biochemical pathways and play a key role in many pathological events and clinical situations. The overall oxidation/reduction (redox) state present in biological compartments is a major target for possible pharmaceutical intervention and, consequently, the processes associated with its change have attracted increased attention in recent years. This overview describes the methods for evaluating the concentrations of redox active compounds and their redoxactivity and the methods for evaluating the overall biological fluids and tissues redox capacity, with a focus on the redox potential parameter, its modulation, its measurement, and its importance for diagnosis and treatment. Examples of voltammetric measurement of reducing power profiles of biological tissues and fluids in healthy and disease states are discussed.

Název v anglickém jazyce

Biological redox activity: Its importance, methods for its quantification and implication for health and disease

Popis výsledku anglicky

Cellular redox phenomena are involved in numerous biochemical pathways and play a key role in many pathological events and clinical situations. The overall oxidation/reduction (redox) state present in biological compartments is a major target for possible pharmaceutical intervention and, consequently, the processes associated with its change have attracted increased attention in recent years. This overview describes the methods for evaluating the concentrations of redox active compounds and their redoxactivity and the methods for evaluating the overall biological fluids and tissues redox capacity, with a focus on the redox potential parameter, its modulation, its measurement, and its importance for diagnosis and treatment. Examples of voltammetric measurement of reducing power profiles of biological tissues and fluids in healthy and disease states are discussed.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2000

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Drug Development Research

ISSN

0272-4391

e-ISSN

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Svazek periodika

50

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

XX - osoby bez státní příslušnosti

Počet stran výsledku

12

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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