Komplexy RuIII s benzyl-disubstituovanými derivátmi 6-benzylaminopurinu

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F07%3A00005592" target="_blank" >RIV/61989592:15310/07:00005592 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

RuIII-complexes involving benzyl-disubstituted derivatives of 6-benzylaminopurine

Popis výsledku v původním jazyce

Many ruthenium-based compounds have been investigated up to now. Among them, a few show interesting biological properties, e.g. [indH][trans-RuIII(ind)2Cl4] (called KP1019), and [ImH][trans-RuIIICl4(DMSO)(Im)] (called NAMI-A). 1,2 This work represents acontinuation in our systematic study of mononuclear RuIII complexes bearing cytokinins derived from 6-benzyalminopurine (L). Generally, we strive to find a relationship between structure and any type of biological activity of the prepared Ru-complexes. Regarding this work, we have prepared octahedral complexes of the composition [trans-RuIIICl4(DMSO)(H+L)] {L = e.g. 6-(2,3-dimethoxybenzylamino)purine}. The compounds have been fully characterized by elemental analysis, IR, VIS and EI+ MS spectroscopies,molar conductivity, cyclic voltammetry, magnetic measurements, and single crystal X-ray analysis. The in vitro cytotoxicity of the complexes against selected human cancer cell lines and SOD-like antiradical activity have also been evaluat

Název v anglickém jazyce

RuIII-complexes involving benzyl-disubstituted derivatives of 6-benzylaminopurine

Popis výsledku anglicky

Many ruthenium-based compounds have been investigated up to now. Among them, a few show interesting biological properties, e.g. [indH][trans-RuIII(ind)2Cl4] (called KP1019), and [ImH][trans-RuIIICl4(DMSO)(Im)] (called NAMI-A). 1,2 This work represents acontinuation in our systematic study of mononuclear RuIII complexes bearing cytokinins derived from 6-benzyalminopurine (L). Generally, we strive to find a relationship between structure and any type of biological activity of the prepared Ru-complexes. Regarding this work, we have prepared octahedral complexes of the composition [trans-RuIIICl4(DMSO)(H+L)] {L = e.g. 6-(2,3-dimethoxybenzylamino)purine}. The compounds have been fully characterized by elemental analysis, IR, VIS and EI+ MS spectroscopies,molar conductivity, cyclic voltammetry, magnetic measurements, and single crystal X-ray analysis. The in vitro cytotoxicity of the complexes against selected human cancer cell lines and SOD-like antiradical activity have also been evaluat

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CA - Anorganická chemie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ChemZi

ISSN

1336-7242

e-ISSN

—

Svazek periodika

3

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

2

Strana od-do

—

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—