N9-Substituted N(6)-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F11%3A10224990" target="_blank" >RIV/61989592:15310/11:10224990 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389030:_____/11:00368655

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.bmc.2011.09.052" target="_blank" >http://dx.doi.org/10.1016/j.bmc.2011.09.052</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.bmc.2011.09.052" target="_blank" >10.1016/j.bmc.2011.09.052</a>

Jazyk výsledku

angličtina

Název v původním jazyce

N9-Substituted N(6)-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays

Popis výsledku v původním jazyce

Rational design is one of the latest ways how to evaluate particular activity of signal molecules, for example cytokinin derivatives. A series of N(6)-[(3-methylbut-2-en-1-yl) amino] purine (iP) derivatives specifically substituted at the N9 atom of purine moiety by tetrahydropyran-2-yl, ethoxyethyl, and C2-C4 alkyl chains terminated by various functional groups were prepared. The reason for this rational design was to reveal the relationship between specific substitution at the N9 atom of purine moietyof iP and cytokinin activity of the prepared compounds. The prepared derivatives were characterized by C, H, N elemental analyses, thin layer chromatography, high performance liquid chromatography, melting point determinations, CI+ mass spectral measurement, and by NMR spectroscopy. Biological activity of prepared compounds was assessed in three in vitro cytokinin bioassays (tobacco callus, wheat leaf senescence, and Amaranthus bioassay).

Název v anglickém jazyce

N9-Substituted N(6)-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays

Popis výsledku anglicky

Rational design is one of the latest ways how to evaluate particular activity of signal molecules, for example cytokinin derivatives. A series of N(6)-[(3-methylbut-2-en-1-yl) amino] purine (iP) derivatives specifically substituted at the N9 atom of purine moiety by tetrahydropyran-2-yl, ethoxyethyl, and C2-C4 alkyl chains terminated by various functional groups were prepared. The reason for this rational design was to reveal the relationship between specific substitution at the N9 atom of purine moietyof iP and cytokinin activity of the prepared compounds. The prepared derivatives were characterized by C, H, N elemental analyses, thin layer chromatography, high performance liquid chromatography, melting point determinations, CI+ mass spectral measurement, and by NMR spectroscopy. Biological activity of prepared compounds was assessed in three in vitro cytokinin bioassays (tobacco callus, wheat leaf senescence, and Amaranthus bioassay).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bioorganic &amp; Medicinal Chemistry

ISSN

0968-0896

e-ISSN

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Svazek periodika

19

Číslo periodika v rámci svazku

23

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

7244-7251

Kód UT WoS článku

000296752300031

EID výsledku v databázi Scopus

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