N9-substituted derivatives of kinetin: Effective anti-senescence agents

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F11%3A10224994" target="_blank" >RIV/61989592:15310/11:10224994 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389030:_____/11:00368599

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.phytochem.2011.02.002" target="_blank" >http://dx.doi.org/10.1016/j.phytochem.2011.02.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.phytochem.2011.02.002" target="_blank" >10.1016/j.phytochem.2011.02.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

N9-substituted derivatives of kinetin: Effective anti-senescence agents

Popis výsledku v původním jazyce

In the present study we prepared a series of eight N9-substituted Kin derivatives, and characterized them with available physicochemical methods such as mass spectrometry and NMR spectroscopy. All compounds were tested in three classical cytokinin bioassays: a tobacco callus assay, an Amaranthus assay, and a senescence assay with excised wheat leaves. The ability of the compounds to interact with Arabidopsis cytokinin receptors CRE1/AHK4 and AHK3 was tested in a bacterial receptor assay. The ability ofcompounds to delay the senescence of excised wheat leaves in both dark and light conditions, was highly correlated with their ability to influence membrane lipid peroxidation, which is a typical symptom of senescence. Our results were corroborated by gene expression profiling of those genes involved in cytokinin metabolism and perception, plant senescence, and the stress response.

Název v anglickém jazyce

N9-substituted derivatives of kinetin: Effective anti-senescence agents

Popis výsledku anglicky

In the present study we prepared a series of eight N9-substituted Kin derivatives, and characterized them with available physicochemical methods such as mass spectrometry and NMR spectroscopy. All compounds were tested in three classical cytokinin bioassays: a tobacco callus assay, an Amaranthus assay, and a senescence assay with excised wheat leaves. The ability of the compounds to interact with Arabidopsis cytokinin receptors CRE1/AHK4 and AHK3 was tested in a bacterial receptor assay. The ability ofcompounds to delay the senescence of excised wheat leaves in both dark and light conditions, was highly correlated with their ability to influence membrane lipid peroxidation, which is a typical symptom of senescence. Our results were corroborated by gene expression profiling of those genes involved in cytokinin metabolism and perception, plant senescence, and the stress response.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Phytochemistry

ISSN

0031-9422

e-ISSN

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Svazek periodika

72

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

821-831

Kód UT WoS článku

000290505500020

EID výsledku v databázi Scopus

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