Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F11%3A33118536" target="_blank" >RIV/61989592:15310/11:33118536 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/jbio.201100073" target="_blank" >http://dx.doi.org/10.1002/jbio.201100073</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jbio.201100073" target="_blank" >10.1002/jbio.201100073</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species

Popis výsledku v původním jazyce

In the human skin, reactive oxygen species (ROS) produced continuously during oxidative metabolic processes (cellular respiration, oxidative burst) are essential for various cellular processes such as defense against infection, cellular signaling and apoptosis. On the other hand, when the formation of ROS exceeds a capacity of the non-enzymatic and the enzymatic antioxidant defense system, ROS cause the damage to the human skin known to initiate premature skin aging and skin cancer. In this study, two-dimensional spontaneous ultra-weak photon emission from the human skin has been measured using a highly sensitive charged coupled device (CCD) camera. It is demonstrated here that two-dimensional ultra-weak photon emission from the human skin increases with the topical application of exogenous ROS in the following order: hydrogen peroxide (H2O2) { superoxide anion radical (O2?-) { hydroxyl radical (HO?). We propose here that the two-dimensional ultra-weak photon emission can be used as a

Název v anglickém jazyce

Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species

Popis výsledku anglicky

In the human skin, reactive oxygen species (ROS) produced continuously during oxidative metabolic processes (cellular respiration, oxidative burst) are essential for various cellular processes such as defense against infection, cellular signaling and apoptosis. On the other hand, when the formation of ROS exceeds a capacity of the non-enzymatic and the enzymatic antioxidant defense system, ROS cause the damage to the human skin known to initiate premature skin aging and skin cancer. In this study, two-dimensional spontaneous ultra-weak photon emission from the human skin has been measured using a highly sensitive charged coupled device (CCD) camera. It is demonstrated here that two-dimensional ultra-weak photon emission from the human skin increases with the topical application of exogenous ROS in the following order: hydrogen peroxide (H2O2) { superoxide anion radical (O2?-) { hydroxyl radical (HO?). We propose here that the two-dimensional ultra-weak photon emission can be used as a

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

<a href="/cs/project/ED0007%2F01%2F01" target="_blank" >ED0007/01/01: Centrum regionu Haná pro biotechnologický a zemědělský výzkum</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Biophotonics

ISSN

1864-063X

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

840-849

Kód UT WoS článku

000297740500006

EID výsledku v databázi Scopus

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