On-line Preconcentration Techniques in Capillary Electrophoresis

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

On-line Preconcentration Techniques in Capillary Electrophoresis

Popis výsledku v původním jazyce

Capillary electrophoresis (CE) represents a high-efficient separation technique which can be used for separation of various types of compounds ranging from low-molecular weight inorganic and organic ions, to structurally big compounds as proteins, nucleic acids or objects as viruses, cells or nanoparticles. However, CE with a conventional UV detector used to suffer from a lack of detection sensitivity since the optical path of the detector is too short. This problem mostly appears if there is a need forseparation of compounds with a biological or medicinal impact (toxicologically important compounds, markers of diseases, metabolites etc.). Fortunately, there is a possibility to overcome this problem by using off-line or on-line preconcentration techniques. The off-line preconcentration techniques (L-L extraction, SPE) are mostly used since they are well-known from other separations as GC or LC. On the other hand, the on-line preconcentration techniques are very interesting because the

Název v anglickém jazyce

On-line Preconcentration Techniques in Capillary Electrophoresis

Popis výsledku anglicky

Capillary electrophoresis (CE) represents a high-efficient separation technique which can be used for separation of various types of compounds ranging from low-molecular weight inorganic and organic ions, to structurally big compounds as proteins, nucleic acids or objects as viruses, cells or nanoparticles. However, CE with a conventional UV detector used to suffer from a lack of detection sensitivity since the optical path of the detector is too short. This problem mostly appears if there is a need forseparation of compounds with a biological or medicinal impact (toxicologically important compounds, markers of diseases, metabolites etc.). Fortunately, there is a possibility to overcome this problem by using off-line or on-line preconcentration techniques. The off-line preconcentration techniques (L-L extraction, SPE) are mostly used since they are well-known from other separations as GC or LC. On the other hand, the on-line preconcentration techniques are very interesting because the

Druh

C - Kapitola v odborné knize

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Capillary Electrophoresis: Fundamentals, Techniques and Applications

ISBN

978-1-62081-785-8

Počet stran výsledku

23

Strana od-do

55-76

Počet stran knihy

266

Název nakladatele

Nova Science Publishers, Inc.

Místo vydání

New York

Kód UT WoS kapitoly

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