Solid-Phase Synthesis Enabling Chemical Diversity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33147704" target="_blank" >RIV/61989592:15310/13:33147704 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Solid-Phase Synthesis Enabling Chemical Diversity

Popis výsledku v původním jazyce

This chapter describes numerous approaches to arriving at diverse compounds using polymer-supported solid-phase synthesis, including skeletal-, stereochemical-, and appendage diversity-generating processes. It focuses mainly on skeletal diversity, due toits great potential to create diverse heterocyclic compounds, although a combination of strategies such as those described in the build/couple/pair (B/C/P) method provides the most promising potential for diversity creation. The critical advantage of the use of solid-phase chemistry for diversity-oriented synthesis (DOS) resides in a potential to build (and synthesize) a large number of very diverse compounds in a relatively short period of time together with the operational simplicity of the process.In addition, chemical diversity can also be achieved by a scaffold hopping process.

Název v anglickém jazyce

Solid-Phase Synthesis Enabling Chemical Diversity

Popis výsledku anglicky

This chapter describes numerous approaches to arriving at diverse compounds using polymer-supported solid-phase synthesis, including skeletal-, stereochemical-, and appendage diversity-generating processes. It focuses mainly on skeletal diversity, due toits great potential to create diverse heterocyclic compounds, although a combination of strategies such as those described in the build/couple/pair (B/C/P) method provides the most promising potential for diversity creation. The critical advantage of the use of solid-phase chemistry for diversity-oriented synthesis (DOS) resides in a potential to build (and synthesize) a large number of very diverse compounds in a relatively short period of time together with the operational simplicity of the process.In addition, chemical diversity can also be achieved by a scaffold hopping process.

Druh

C - Kapitola v odborné knize

CEP obor

CC - Organická chemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Diversity-Oriented Synthesis: Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

ISBN

978-1-118-14565-4

Počet stran výsledku

52

Strana od-do

201-252

Počet stran knihy

629

Název nakladatele

John Wiley & Sons, Inc.

Místo vydání

USA

Kód UT WoS kapitoly

—