Antimicrobial peptide production and plant-based expression systems for medical and agricultural biotechnology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33155788" target="_blank" >RIV/61989592:15310/15:33155788 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0734975015000579" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0734975015000579</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biotechadv.2015.03.007" target="_blank" >10.1016/j.biotechadv.2015.03.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antimicrobial peptide production and plant-based expression systems for medical and agricultural biotechnology

Popis výsledku v původním jazyce

Antimicrobial peptides (AMPs) are vital components of the innate immune system of nearly all living organisms. They generally act in the ?rst line of defense against various pathogenic bacteria, parasites, enveloped viruses and fungi. These low molecularmass peptides are considered prospective therapeutic agents due to their broad-spectrum rapid activity, low cytotoxicity to mammalian cells and unique mode of action which hinders emergence of pathogen resistance. In addition to medical use, AMPs can also be employed for development of innovative approaches for plant protection in agriculture. Conferred disease resistance by AMPs might help us surmount losses in yield, quality and safety of agricultural products due to plant pathogens. Heterologous expres- sion in plant-based systems, also called plant molecular farming, offers cost-effective large-scale production which is regarded as one of the most important factors for clinical or agricultural use of AMPs. This review presents vari

Název v anglickém jazyce

Antimicrobial peptide production and plant-based expression systems for medical and agricultural biotechnology

Popis výsledku anglicky

Antimicrobial peptides (AMPs) are vital components of the innate immune system of nearly all living organisms. They generally act in the ?rst line of defense against various pathogenic bacteria, parasites, enveloped viruses and fungi. These low molecularmass peptides are considered prospective therapeutic agents due to their broad-spectrum rapid activity, low cytotoxicity to mammalian cells and unique mode of action which hinders emergence of pathogen resistance. In addition to medical use, AMPs can also be employed for development of innovative approaches for plant protection in agriculture. Conferred disease resistance by AMPs might help us surmount losses in yield, quality and safety of agricultural products due to plant pathogens. Heterologous expres- sion in plant-based systems, also called plant molecular farming, offers cost-effective large-scale production which is regarded as one of the most important factors for clinical or agricultural use of AMPs. This review presents vari

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

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Projekt

<a href="/cs/project/LO1204" target="_blank" >LO1204: Udržitelný rozvoj výzkumu v Centru regionu Haná</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biotechnology Advances

ISSN

0734-9750

e-ISSN

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Svazek periodika

33

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

19

Strana od-do

1005-1023

Kód UT WoS článku

000362380100003

EID výsledku v databázi Scopus

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