Fast separation of selected cathinones and phenylethylamines by supercritical fluid chromatography

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33156851" target="_blank" >RIV/61989592:15310/15:33156851 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388971:_____/15:00464011

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S002196731501540X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S002196731501540X</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2015.10.061" target="_blank" >10.1016/j.chroma.2015.10.061</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fast separation of selected cathinones and phenylethylamines by supercritical fluid chromatography

Popis výsledku v původním jazyce

The chromatographic behaviour of eleven synthetic cathinones and four phenylethylamines under supercritical/subcritical fluid conditions was investigated. Four stationary phases with sub-2 mu m particles (Waters Acquity UPC2 BEH silica, BEH 2-ethylpyridine, CSH Fluoro-Phenyl, and HSS C18SB) were evaluated in terms of isomer resolution, chromatographic peak shape, and analysis time. Methanol, water, formic acid, ammonium hydroxide, ammonium acetate, and ammonium formate were mixed with carbon dioxide totest their influence on analyte retention and peak shapes. Methanol and ammonium cations were essential for successful separations. Efficient separations of four isomeric pairs (R > 1), and most of the remaining analytes, were achieved in less than 3.3 min on BEH and Fluoro-Phenyl columns with gradient of methanolic ammonium hydroxide in CO2. Drugs were detected by positive electrospray ionization triple quadrupole mass spectrometry in selected reaction monitoring mode. Added detection s

Název v anglickém jazyce

Fast separation of selected cathinones and phenylethylamines by supercritical fluid chromatography

Popis výsledku anglicky

The chromatographic behaviour of eleven synthetic cathinones and four phenylethylamines under supercritical/subcritical fluid conditions was investigated. Four stationary phases with sub-2 mu m particles (Waters Acquity UPC2 BEH silica, BEH 2-ethylpyridine, CSH Fluoro-Phenyl, and HSS C18SB) were evaluated in terms of isomer resolution, chromatographic peak shape, and analysis time. Methanol, water, formic acid, ammonium hydroxide, ammonium acetate, and ammonium formate were mixed with carbon dioxide totest their influence on analyte retention and peak shapes. Methanol and ammonium cations were essential for successful separations. Efficient separations of four isomeric pairs (R > 1), and most of the remaining analytes, were achieved in less than 3.3 min on BEH and Fluoro-Phenyl columns with gradient of methanolic ammonium hydroxide in CO2. Drugs were detected by positive electrospray ionization triple quadrupole mass spectrometry in selected reaction monitoring mode. Added detection s

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/LH14064" target="_blank" >LH14064: Analytické nástroje pro rychlou identifikaci nových syntetických drog</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A: Symposium Volumes

ISSN

0021-9673

e-ISSN

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Svazek periodika

1423

Číslo periodika v rámci svazku

DEC

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

169-176

Kód UT WoS článku

000366073000019

EID výsledku v databázi Scopus

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