S-nitrosoglutathione reductase: a key regulator of S-nitrosylation in plant development and stress responses

Kód výsledku v IS VaVaI

RIV/61989592:15310/15:33156952 - isvavai.cz

Výsledek na webu

http://dx.doi.org/10.1007/978-3-319-10079-1_14

DOI - Digital Object Identifier

10.1007/978-3-319-10079-1_14

Jazyk výsledku

angličtina

Název v původním jazyce

S-nitrosoglutathione reductase: a key regulator of S-nitrosylation in plant development and stress responses

Popis výsledku v původním jazyce

S-nitrosylation has emerged recently as a new type of ubiquitous protein posttranslational modification, based on the attachment of nitroso group to cysteine thiols. S-nitrosothiols represent relatively stable and mobile reservoir of nitric oxide bioactivity, and are viewed as a convergence of signalling pathways of reactive nitrogen (RNS) and oxygen (ROS) species. This review summarizes actual knowledge on S-nitrosoglutathione reductase (GSNOR), considered a key enzyme of the regulation of intracellular levels of S-nitrosoglutathione and indirectly also of protein S-nitrosothiols. The biological functions of GSNOR are mediated by its capacity to catalyse irreversible GSNO decomposition to oxidised glutathione as a part of nitric oxide catabolism. GSNOR is required for to maintain balanced levels of ROS and RNS and participate in the overall control of cell redox state. Altered expression and levels of GSNOR have been found associated with important pathological processes in animals. G

Název v anglickém jazyce

S-nitrosoglutathione reductase: a key regulator of S-nitrosylation in plant development and stress responses

Popis výsledku anglicky

S-nitrosylation has emerged recently as a new type of ubiquitous protein posttranslational modification, based on the attachment of nitroso group to cysteine thiols. S-nitrosothiols represent relatively stable and mobile reservoir of nitric oxide bioactivity, and are viewed as a convergence of signalling pathways of reactive nitrogen (RNS) and oxygen (ROS) species. This review summarizes actual knowledge on S-nitrosoglutathione reductase (GSNOR), considered a key enzyme of the regulation of intracellular levels of S-nitrosoglutathione and indirectly also of protein S-nitrosothiols. The biological functions of GSNOR are mediated by its capacity to catalyse irreversible GSNO decomposition to oxidised glutathione as a part of nitric oxide catabolism. GSNOR is required for to maintain balanced levels of ROS and RNS and participate in the overall control of cell redox state. Altered expression and levels of GSNOR have been found associated with important pathological processes in animals. G

Druh

C - Kapitola v odborné knize

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

LH11013: S-nitrosoglutathionreduktasa: klíčový enzym regulace metabolismu oxidu dusnatého v rostlinách a jeho funkce v odpovědi rostlin na stresové podmínky

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Reactive Oxygen and Nitrogen Species Signaling and Communication in Plants

ISBN

978-3-319-10078-4

Počet stran výsledku

17

Strana od-do

283-299

Počet stran knihy

316

Název nakladatele

Springer

Místo vydání

Heidelberg

Kód UT WoS kapitoly

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