High Performance Liquid Chromatography/Electrochemistry/High Resolution Electrospray Ionization-Mass Spectrometry (HPLC/EC/HR ESI-MS) Characterization of Selected Cytokinins Oxidation Products
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33157498" target="_blank" >RIV/61989592:15310/15:33157498 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61389030:_____/15:00446194
Výsledek na webu
<a href="http://onlinelibrary.wiley.com/doi/10.1002/elan.201400286/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/elan.201400286/epdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elan.201400286" target="_blank" >10.1002/elan.201400286</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
High Performance Liquid Chromatography/Electrochemistry/High Resolution Electrospray Ionization-Mass Spectrometry (HPLC/EC/HR ESI-MS) Characterization of Selected Cytokinins Oxidation Products
Popis výsledku v původním jazyce
Electrochemistry combined with mass spectrometry represents an emerging analytical technique used to study the oxidation pathway of various drugs and in vivo occurring compounds, continuously showing a capability to generate many known metabolites or newoxidation products. An on-line HPLC/EC/HR ESI-MS method had been used to investigate the oxidation of selected cytokinin compounds. This setup allowed rapid identification and general structure elucidation of the obtained products. An electrochemical oxidation of isopentenyladenine resulted in five products, including hydroxylated and dehydrogenated products, which correlates very well with its in vivo metabolism. Electrochemical conversion of trans-zeatin revealed six products, with two dehydrogenation products corresponding to its in vivo occurring metabolites. cis-Zeatin oxidation in the electrochemical cell gave rise to eight products, resembling similarity to trans-zeatin oxidation. All three compounds underwent a complete turnove
Název v anglickém jazyce
High Performance Liquid Chromatography/Electrochemistry/High Resolution Electrospray Ionization-Mass Spectrometry (HPLC/EC/HR ESI-MS) Characterization of Selected Cytokinins Oxidation Products
Popis výsledku anglicky
Electrochemistry combined with mass spectrometry represents an emerging analytical technique used to study the oxidation pathway of various drugs and in vivo occurring compounds, continuously showing a capability to generate many known metabolites or newoxidation products. An on-line HPLC/EC/HR ESI-MS method had been used to investigate the oxidation of selected cytokinin compounds. This setup allowed rapid identification and general structure elucidation of the obtained products. An electrochemical oxidation of isopentenyladenine resulted in five products, including hydroxylated and dehydrogenated products, which correlates very well with its in vivo metabolism. Electrochemical conversion of trans-zeatin revealed six products, with two dehydrogenation products corresponding to its in vivo occurring metabolites. cis-Zeatin oxidation in the electrochemical cell gave rise to eight products, resembling similarity to trans-zeatin oxidation. All three compounds underwent a complete turnove
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CB - Analytická chemie, separace
OECD FORD obor
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Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Electroanalysis
ISSN
1040-0397
e-ISSN
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Svazek periodika
27
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
9
Strana od-do
406-414
Kód UT WoS článku
000349558900018
EID výsledku v databázi Scopus
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