Seasonal pharmacological properties and alkaloid content in Cyrtanthus contractus NE Br.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33157520" target="_blank" >RIV/61989592:15310/15:33157520 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389030:_____/15:00446274

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0254629914002294" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0254629914002294</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.sajb.2014.12.005" target="_blank" >10.1016/j.sajb.2014.12.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Seasonal pharmacological properties and alkaloid content in Cyrtanthus contractus NE Br.

Popis výsledku v původním jazyce

Representatives of the genus Cyrtanthus including Cyrtanthus contractus of the Amaryllidaceae family are widely used in African traditional medicine for the treatment of a range of ailments, including mental illness and age-related dementia. The alkaloidconstituents distributed within the genus, which are chiefly responsible for the biological activity of the derived extracts, are thought to be influenced by changes in the growing environment. Natural growing populations of C. contractus were tagged and collected every 15th day of each month over a 12 month period. The ethanol bulb extracts from each of the collected samples were evaluated for total alkaloid content, cytotoxic effects, acetylcholinesterase and cyclooxygenase inhibition as well as antimicrobial activities. Some notable bioactivities were recorded for extracts collected during certain months of the year, particularly the cytotoxic effects against human cancer cell lines and enzyme inhibition (AChE and COX). The cytotoxi

Název v anglickém jazyce

Seasonal pharmacological properties and alkaloid content in Cyrtanthus contractus NE Br.

Popis výsledku anglicky

Representatives of the genus Cyrtanthus including Cyrtanthus contractus of the Amaryllidaceae family are widely used in African traditional medicine for the treatment of a range of ailments, including mental illness and age-related dementia. The alkaloidconstituents distributed within the genus, which are chiefly responsible for the biological activity of the derived extracts, are thought to be influenced by changes in the growing environment. Natural growing populations of C. contractus were tagged and collected every 15th day of each month over a 12 month period. The ethanol bulb extracts from each of the collected samples were evaluated for total alkaloid content, cytotoxic effects, acetylcholinesterase and cyclooxygenase inhibition as well as antimicrobial activities. Some notable bioactivities were recorded for extracts collected during certain months of the year, particularly the cytotoxic effects against human cancer cell lines and enzyme inhibition (AChE and COX). The cytotoxi

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EF - Botanika

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

South African Journal of Botany

ISSN

0254-6299

e-ISSN

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Svazek periodika

2015

Číslo periodika v rámci svazku

97

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

69-76

Kód UT WoS článku

000350654800009

EID výsledku v databázi Scopus

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