Antimicrobial peptides: a key component of honey bee innate immunity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33157836" target="_blank" >RIV/61989592:15310/15:33157836 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1080/00218839.2015.1109919" target="_blank" >http://dx.doi.org/10.1080/00218839.2015.1109919</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/00218839.2015.1109919" target="_blank" >10.1080/00218839.2015.1109919</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antimicrobial peptides: a key component of honey bee innate immunity

Popis výsledku v původním jazyce

Honey bee immune responses are composed of a complex suite of individual immune mechanisms and special types of behavioral adaptations. The main focus of this paper is innate immunity in the honey bee, and specifically, the role and function of antimicrobial peptides (AMPs). Insect innate immunity constitutes evolutionary conserved defense strategies that provide immediate responses against invading pathogens. It consists of the three levels of resistance: physical barriers as the first line of defense,cell-mediated immunity, and cell-free humoral immunity, a complex network of intracellular signaling pathways leading to activation of a variety of humoral factors. Among those, AMPs are recognized as key components of humoral immunity in many types oforganisms. The two basic mechanisms of action are: (1) the generation of leaks into prokaryotic membranes; and (2) either inhibition of bacterial protein translation or folding. Recently, four families of AMPs (i.e., apidaecins, abaecin,

Název v anglickém jazyce

Antimicrobial peptides: a key component of honey bee innate immunity

Popis výsledku anglicky

Honey bee immune responses are composed of a complex suite of individual immune mechanisms and special types of behavioral adaptations. The main focus of this paper is innate immunity in the honey bee, and specifically, the role and function of antimicrobial peptides (AMPs). Insect innate immunity constitutes evolutionary conserved defense strategies that provide immediate responses against invading pathogens. It consists of the three levels of resistance: physical barriers as the first line of defense,cell-mediated immunity, and cell-free humoral immunity, a complex network of intracellular signaling pathways leading to activation of a variety of humoral factors. Among those, AMPs are recognized as key components of humoral immunity in many types oforganisms. The two basic mechanisms of action are: (1) the generation of leaks into prokaryotic membranes; and (2) either inhibition of bacterial protein translation or folding. Recently, four families of AMPs (i.e., apidaecins, abaecin,

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Apicultural Research

ISSN

0021-8839

e-ISSN

—

Svazek periodika

54

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

123-136

Kód UT WoS článku

000371247400010

EID výsledku v databázi Scopus

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