Does EmbryoGlue transfer medium affect embryo transfer success rate?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F18%3A73606580" target="_blank" >RIV/61989592:15310/18:73606580 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.prolekare.cz/casopisy/ceska-gynekologie/2018-3-12/ovlivnuje-pouziti-transferoveho-media-embryoglue-uspesnost-embryotransferu-105711" target="_blank" >https://www.prolekare.cz/casopisy/ceska-gynekologie/2018-3-12/ovlivnuje-pouziti-transferoveho-media-embryoglue-uspesnost-embryotransferu-105711</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Does EmbryoGlue transfer medium affect embryo transfer success rate?

Popis výsledku v původním jazyce

Objective: Verification of the effect of EmbryoGlue (EG) transfer medium enriched with hyaluronan on the embryo transfer success rate. Design: A prospective study. Setting: Fertimed, Fertility Treatment Centre, Olomouc. Methods: 484 patients undergoing IVF + ET were engaged who were divided according to the medium used during transfer: Sage or Vitrolife culture medium (n = 135) and EG transfer medium (n = 349). The influence of other factors was also evaluated: age, number of received oocytes, percentage of fertilised oocytes, endometrium height on the day of transfer, number of preserved embryos, number of transferred embryos and the length of cultivation (48, 72, 96, 120 h). These factors were considered quantitative variables while the method of hormone stimulation, the type of culture medium and the application of EG were considered qualitative (categorical) variables. Results: With the use of EG the chances of conception increased by approximately 9%. The negative effect of higher age on implantation proportion and the positive effect of cultivation prolongation were proven. The effect of EG on miscarriages was not proven. The probability of miscarriage diminished with higher oocyte fertilisation. The culture medium used (Sage or Vitrolife) before the application of EG does not affect the gravidity result. Conclusion: Using the transfer medium of EmbryoGlue before embryo transfer affects the pregnancy rate (PR) in a positive manner. The influence on pregnancy loss with the application of EG was not proven.

Název v anglickém jazyce

Does EmbryoGlue transfer medium affect embryo transfer success rate?

Popis výsledku anglicky

Objective: Verification of the effect of EmbryoGlue (EG) transfer medium enriched with hyaluronan on the embryo transfer success rate. Design: A prospective study. Setting: Fertimed, Fertility Treatment Centre, Olomouc. Methods: 484 patients undergoing IVF + ET were engaged who were divided according to the medium used during transfer: Sage or Vitrolife culture medium (n = 135) and EG transfer medium (n = 349). The influence of other factors was also evaluated: age, number of received oocytes, percentage of fertilised oocytes, endometrium height on the day of transfer, number of preserved embryos, number of transferred embryos and the length of cultivation (48, 72, 96, 120 h). These factors were considered quantitative variables while the method of hormone stimulation, the type of culture medium and the application of EG were considered qualitative (categorical) variables. Results: With the use of EG the chances of conception increased by approximately 9%. The negative effect of higher age on implantation proportion and the positive effect of cultivation prolongation were proven. The effect of EG on miscarriages was not proven. The probability of miscarriage diminished with higher oocyte fertilisation. The culture medium used (Sage or Vitrolife) before the application of EG does not affect the gravidity result. Conclusion: Using the transfer medium of EmbryoGlue before embryo transfer affects the pregnancy rate (PR) in a positive manner. The influence on pregnancy loss with the application of EG was not proven.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

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OECD FORD obor

10604 - Reproductive biology (medical aspects to be 3)

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ceska Gynekologie-Czech Gynaecology

ISSN

1210-7832

e-ISSN

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Svazek periodika

83

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

177-181

Kód UT WoS článku

000458872400003

EID výsledku v databázi Scopus

2-s2.0-85056076920