Plant molecular farming: production of metallic nanoparticles and therapeutic proteins using green factories

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F19%3A73595364" target="_blank" >RIV/61989592:15310/19:73595364 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.rsc.org/en/content/articlehtml/2019/gc/c9gc00335e" target="_blank" >https://pubs.rsc.org/en/content/articlehtml/2019/gc/c9gc00335e</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c9gc00335e" target="_blank" >10.1039/c9gc00335e</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Plant molecular farming: production of metallic nanoparticles and therapeutic proteins using green factories

Popis výsledku v původním jazyce

Plants have had numerous biological, clinical, pharmaceutical and medicinal purposes for many years; however, their use as a general platform for preparation of desired pharmaceutical and biomedical compounds is relatively current. Secondary metabolites with remarkable and diverse biological functions are produced by medicinal plants. Significant advancements in nanosciences have enabled their various applications in the development of a new generation of drug molecules. Due to the application of toxic solvents and high energy consumption of conventional physical and chemical approaches, greener and eco-friendly methods are essential and vital. Plants can provide an outstanding alternative for the production of phytomaterials and biomaterials, and this review highlights the exogenous and endogenous syntheses of nanoparticles using living plants. Additionally, the plant nano-molecular farming of proteins including collagen, gelatin, elastin, recombinant anti-cancer monoclonal antibodies and recombinant anti-cancer vaccines is discussed.

Název v anglickém jazyce

Plant molecular farming: production of metallic nanoparticles and therapeutic proteins using green factories

Popis výsledku anglicky

Plants have had numerous biological, clinical, pharmaceutical and medicinal purposes for many years; however, their use as a general platform for preparation of desired pharmaceutical and biomedical compounds is relatively current. Secondary metabolites with remarkable and diverse biological functions are produced by medicinal plants. Significant advancements in nanosciences have enabled their various applications in the development of a new generation of drug molecules. Due to the application of toxic solvents and high energy consumption of conventional physical and chemical approaches, greener and eco-friendly methods are essential and vital. Plants can provide an outstanding alternative for the production of phytomaterials and biomaterials, and this review highlights the exogenous and endogenous syntheses of nanoparticles using living plants. Additionally, the plant nano-molecular farming of proteins including collagen, gelatin, elastin, recombinant anti-cancer monoclonal antibodies and recombinant anti-cancer vaccines is discussed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21002 - Nano-processes (applications on nano-scale); (biomaterials to be 2.9)

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

GREEN CHEMISTRY

ISSN

1463-9262

e-ISSN

—

Svazek periodika

21

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

21

Strana od-do

1845-1865

Kód UT WoS článku

000465398000001

EID výsledku v databázi Scopus

2-s2.0-85064561545