Cytokinin Signalling and Mechanism of Action of Meta-Topolin and Its Derivatives

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F21%3A73610643" target="_blank" >RIV/61989592:15310/21:73610643 - isvavai.cz</a>

Výsledek na webu

<a href="https://obd.upol.cz/id_publ/333190530" target="_blank" >https://obd.upol.cz/id_publ/333190530</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-981-15-9046-7_5" target="_blank" >10.1007/978-981-15-9046-7_5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cytokinin Signalling and Mechanism of Action of Meta-Topolin and Its Derivatives

Popis výsledku v původním jazyce

The discovery of ortho-topolin, meta-topolin and its conjugates in the early 1990s prompted further research on the biological activity of these aromatic cytokinins. Structure–activity relationship studies (SAR) revealed that hydroxylation at the meta-position on the benzyl side chain of BAP and its riboside significantly improved the compound performance in standardized cytokinin bioassays compared to BAP. Elucidation of the molecular mechanism of the cytokinin signal transduction and identification of membrane-bound receptor histidine kinase (HK) led to deeper understanding of the function of topolins in planta. While aromatic cytokinins generally show weak interaction with Arabidopsis and other cytokinin-sensitive HKs, meta-topolin is able to provoke a strong response comparable to that observed with the most active isoprenoid free bases. In contrast, ortho-topolin and para-topolin are much less active, and it is possible that hydroxylation at these positions serves as a deactivation step. In contrast, derivatives of meta-topolin, although not directly interacting with cytokinin-sensitive HKs, have proven to be very useful in plant propagation techniques, and slow gradual release of the free active base allows for the potentiation of cytokinin effects. This chapter summarizes basic facts about cytokinin signalling and adds to our knowledge of signalling aspects and metabolism of aromatic cytokinins in various plant models.

Název v anglickém jazyce

Cytokinin Signalling and Mechanism of Action of Meta-Topolin and Its Derivatives

Popis výsledku anglicky

The discovery of ortho-topolin, meta-topolin and its conjugates in the early 1990s prompted further research on the biological activity of these aromatic cytokinins. Structure–activity relationship studies (SAR) revealed that hydroxylation at the meta-position on the benzyl side chain of BAP and its riboside significantly improved the compound performance in standardized cytokinin bioassays compared to BAP. Elucidation of the molecular mechanism of the cytokinin signal transduction and identification of membrane-bound receptor histidine kinase (HK) led to deeper understanding of the function of topolins in planta. While aromatic cytokinins generally show weak interaction with Arabidopsis and other cytokinin-sensitive HKs, meta-topolin is able to provoke a strong response comparable to that observed with the most active isoprenoid free bases. In contrast, ortho-topolin and para-topolin are much less active, and it is possible that hydroxylation at these positions serves as a deactivation step. In contrast, derivatives of meta-topolin, although not directly interacting with cytokinin-sensitive HKs, have proven to be very useful in plant propagation techniques, and slow gradual release of the free active base allows for the potentiation of cytokinin effects. This chapter summarizes basic facts about cytokinin signalling and adds to our knowledge of signalling aspects and metabolism of aromatic cytokinins in various plant models.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

<a href="/cs/project/EF17_048%2F0007323" target="_blank" >EF17_048/0007323: Rozvoj předaplikačního výzkumu v oblasti nano- a biotechnologií</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture

ISBN

978-981-15-9045-0

Počet stran výsledku

10

Strana od-do

39-48

Počet stran knihy

339

Název nakladatele

Springer

Místo vydání

Singapore

Kód UT WoS kapitoly

—