Intraocular pressure response to gradual onset of extreme normobaric hypoxia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F24%3A73625324" target="_blank" >RIV/61989592:15310/24:73625324 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15510/24:73625324

Výsledek na webu

<a href="https://www.minervamedica.it/en/journals/medicina-dello-sport/article.php?cod=R26Y2024N01A0037" target="_blank" >https://www.minervamedica.it/en/journals/medicina-dello-sport/article.php?cod=R26Y2024N01A0037</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23736/S0025-7826.24.04397-7" target="_blank" >10.23736/S0025-7826.24.04397-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Intraocular pressure response to gradual onset of extreme normobaric hypoxia

Popis výsledku v původním jazyce

BACKGROUND: During many sports, the organism is exposed to hypoxia. Exposure to hypoxia, such as staying at high altitudes, affects intraocular pressure (IOP), which is one of the most monitored parameters connected with glaucoma. This paper assesses the IOP response to a gradual onset of normobaric hypoxia and its acute termination. METHODS: Thirty-six subjects (2911 years) performed the complete test. The observed parameters were IOP, arterial oxygen saturation and corneal thickness (CT). After measurements in normoxia, subjects entered a normobaric hypoxic chamber with a simulated altitude of 2000 m which increased up to 5000 m during 77±7 min. After exposure (18±2 min) in the final altitude, the subjects left the chamber. RESULTS: The IOP significantly dropped after leaving the chamber up to 15.7±2.7 mmHg in comparison with the simulated altitude 5000 m (17.5±3.4 mmHg). The step change from normoxia to a simulated altitude (2000 m) and its gradual increase up to 5000 m did not affect IOP significantly. The CT did not change during the experiment. CONCLUSIONS: Gradual increase in hypoxia over tens of minutes does not affect IOP significantly, whereas a sudden departure from the hypoxic chamber with a simulated altitude of 5000 m causes significant changes in IOP. This IOP variation could be potentially health issue e.g. for glaucoma patients.

Název v anglickém jazyce

Intraocular pressure response to gradual onset of extreme normobaric hypoxia

Popis výsledku anglicky

BACKGROUND: During many sports, the organism is exposed to hypoxia. Exposure to hypoxia, such as staying at high altitudes, affects intraocular pressure (IOP), which is one of the most monitored parameters connected with glaucoma. This paper assesses the IOP response to a gradual onset of normobaric hypoxia and its acute termination. METHODS: Thirty-six subjects (2911 years) performed the complete test. The observed parameters were IOP, arterial oxygen saturation and corneal thickness (CT). After measurements in normoxia, subjects entered a normobaric hypoxic chamber with a simulated altitude of 2000 m which increased up to 5000 m during 77±7 min. After exposure (18±2 min) in the final altitude, the subjects left the chamber. RESULTS: The IOP significantly dropped after leaving the chamber up to 15.7±2.7 mmHg in comparison with the simulated altitude 5000 m (17.5±3.4 mmHg). The step change from normoxia to a simulated altitude (2000 m) and its gradual increase up to 5000 m did not affect IOP significantly. The CT did not change during the experiment. CONCLUSIONS: Gradual increase in hypoxia over tens of minutes does not affect IOP significantly, whereas a sudden departure from the hypoxic chamber with a simulated altitude of 5000 m causes significant changes in IOP. This IOP variation could be potentially health issue e.g. for glaucoma patients.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MEDICINA DELLO SPORT

ISSN

0025-7826

e-ISSN

1827-1863

Svazek periodika

77

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

11

Strana od-do

37-47

Kód UT WoS článku

001229402100013

EID výsledku v databázi Scopus

2-s2.0-85189703930