Concentration of soluble leptin receptor in population

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15510%2F00%3A00000060" target="_blank" >RIV/61989592:15510/00:00000060 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Concentration of soluble leptin receptor in population

Popis výsledku v původním jazyce

Examinations were performed in 568 probands (217 men, 351 women) selected randomly from healthy population according to the following criterion: no treatment in the last six weeks for any disease. All probands were subjected to determination of BMI, cholesterol, triacylglycerols, LDL-cholesterol, intact proinsulin, insulin, uric acid, ALT, AST, GMT, LD, CRP, aterogenic plasma index, leptin and soluble leptin receptor. We determined cncentration of soluble leptin receptor in population sample of 560 probands. A positive correlation between leptinemia and BMI value was confirmed. It was found that Ob-Re concentration did not correlate with common anthropometrical parameters nor leptin concentration in the serum, but correlated negatively only with insulin and plasma aterogenity. This finding indicates presence of free leptin in patients with signs of insulin (therefore also leptin) resistance.

Název v anglickém jazyce

Concentration of soluble leptin receptor in population

Popis výsledku anglicky

Examinations were performed in 568 probands (217 men, 351 women) selected randomly from healthy population according to the following criterion: no treatment in the last six weeks for any disease. All probands were subjected to determination of BMI, cholesterol, triacylglycerols, LDL-cholesterol, intact proinsulin, insulin, uric acid, ALT, AST, GMT, LD, CRP, aterogenic plasma index, leptin and soluble leptin receptor. We determined cncentration of soluble leptin receptor in population sample of 560 probands. A positive correlation between leptinemia and BMI value was confirmed. It was found that Ob-Re concentration did not correlate with common anthropometrical parameters nor leptin concentration in the serum, but correlated negatively only with insulin and plasma aterogenity. This finding indicates presence of free leptin in patients with signs of insulin (therefore also leptin) resistance.

Druh

C - Kapitola v odborné knize

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2000

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Acta Universitatis Palackianae Olomucensis. Facultas Medicae. Biomedical Papers

ISBN

0862-481X

Počet stran výsledku

93

Strana od-do

—

Počet stran knihy

—

Název nakladatele

Vydavatelství Univerzity Palackého

Místo vydání

Olomouc

Kód UT WoS kapitoly

—