Antibacterial and wound healing activities of silver nanoparticles embedded in cellulose compared to other polysaccharides and protein polymers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15640%2F21%3A73612337" target="_blank" >RIV/61989592:15640/21:73612337 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s10570-021-04067-3" target="_blank" >https://link.springer.com/article/10.1007/s10570-021-04067-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10570-021-04067-3" target="_blank" >10.1007/s10570-021-04067-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antibacterial and wound healing activities of silver nanoparticles embedded in cellulose compared to other polysaccharides and protein polymers

Popis výsledku v původním jazyce

The aggregation of silver nanoparticles (AgNPs) in colloidal solution and the oxidative cytotoxicity towards human cells are two major hindrances for their thriving medicinal applications. Their incorporation in natural polymers such as cellulose, chitosan, alginate, collagen, gelatin, silk fibroin, carrageenan, curdlan, hyaluronic acid, keratin and starch may be an alluring alternative strategy to sidestep these complications and attain advantageous wound dressings. Biocompatibility, bioavailability, biodegradability, and inherent therapeutic properties known for such polymers, would accelerate the healing of infected chronic wounds. However, the low thermal stability, mechanical strength, rapid biodegradation, and weak washing resistance properties are some of the limitations for these polymers. Herein, recent advances, present challenges, and future perspectives for AgNPs-incorporated nanocomposites (NCs) are discussed to realize the ideal antibacterial activities by exploiting the abundant natural biopolymers.

Název v anglickém jazyce

Antibacterial and wound healing activities of silver nanoparticles embedded in cellulose compared to other polysaccharides and protein polymers

Popis výsledku anglicky

The aggregation of silver nanoparticles (AgNPs) in colloidal solution and the oxidative cytotoxicity towards human cells are two major hindrances for their thriving medicinal applications. Their incorporation in natural polymers such as cellulose, chitosan, alginate, collagen, gelatin, silk fibroin, carrageenan, curdlan, hyaluronic acid, keratin and starch may be an alluring alternative strategy to sidestep these complications and attain advantageous wound dressings. Biocompatibility, bioavailability, biodegradability, and inherent therapeutic properties known for such polymers, would accelerate the healing of infected chronic wounds. However, the low thermal stability, mechanical strength, rapid biodegradation, and weak washing resistance properties are some of the limitations for these polymers. Herein, recent advances, present challenges, and future perspectives for AgNPs-incorporated nanocomposites (NCs) are discussed to realize the ideal antibacterial activities by exploiting the abundant natural biopolymers.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CELLULOSE

ISSN

0969-0239

e-ISSN

—

Svazek periodika

28

Číslo periodika v rámci svazku

13

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

17

Strana od-do

8295-8311

Kód UT WoS článku

000672273000003

EID výsledku v databázi Scopus

2-s2.0-85110732377