Heterogeneous catalyzed N-alkylation of amines with alcohols via borrowing hydrogen methodology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15640%2F25%3A73631033" target="_blank" >RIV/61989592:15640/25:73631033 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27640/25:10257951

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0010854525003200?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0010854525003200?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ccr.2025.216750" target="_blank" >10.1016/j.ccr.2025.216750</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Heterogeneous catalyzed N-alkylation of amines with alcohols via borrowing hydrogen methodology

Popis výsledku v původním jazyce

The synthesis and functionalization of amines by catalytic N-alkylations using alcohols via the borrowing hydrogen strategy is an environmentally friendly and atom-economical process, in which water is produced as the only by-product. To perform these reactions more efficiently and selectively, the design and applicability of suitable catalysts are prerequisites and of paramount importance. More specifically, heterogeneous catalysts are preferred for the advancement of the amine synthetic process due to the inherited advantages of these materials in terms of stability, recyclability and reusability. In addition, utilizing biomass-derived alcohols as alkylating agents to produce N-alkylated amines is of increasing importance with respect to the valorization of renewable feedstocks, which represent an alternative and potentially competitive approach to fossil-based feedstocks. Herein, we comprehensively review the research progress on the N-alkylation of various amines (e.g., ammonia, primary amines, secondary amines) as well as amides, and sulfonamides with alcohols as potential alkylating agents via the borrowing hydrogen strategy using heterogeneous catalysts under thermal and photochemical conditions. Additionally, synesthetic approaches for catalyst design, reaction mechanism and their structureperformance relationship are discussed. Moreover, advanced in situ characterization and density functional theory (DFT) studies are emphasized to comprehend the reaction pathways and mechanisms involved in the thermocatalytic and photocatalytic N-alkylation of amines with alcohols. Finally, we highlight the current challenges and future opportunities within this attractive field.

Název v anglickém jazyce

Heterogeneous catalyzed N-alkylation of amines with alcohols via borrowing hydrogen methodology

Popis výsledku anglicky

The synthesis and functionalization of amines by catalytic N-alkylations using alcohols via the borrowing hydrogen strategy is an environmentally friendly and atom-economical process, in which water is produced as the only by-product. To perform these reactions more efficiently and selectively, the design and applicability of suitable catalysts are prerequisites and of paramount importance. More specifically, heterogeneous catalysts are preferred for the advancement of the amine synthetic process due to the inherited advantages of these materials in terms of stability, recyclability and reusability. In addition, utilizing biomass-derived alcohols as alkylating agents to produce N-alkylated amines is of increasing importance with respect to the valorization of renewable feedstocks, which represent an alternative and potentially competitive approach to fossil-based feedstocks. Herein, we comprehensively review the research progress on the N-alkylation of various amines (e.g., ammonia, primary amines, secondary amines) as well as amides, and sulfonamides with alcohols as potential alkylating agents via the borrowing hydrogen strategy using heterogeneous catalysts under thermal and photochemical conditions. Additionally, synesthetic approaches for catalyst design, reaction mechanism and their structureperformance relationship are discussed. Moreover, advanced in situ characterization and density functional theory (DFT) studies are emphasized to comprehend the reaction pathways and mechanisms involved in the thermocatalytic and photocatalytic N-alkylation of amines with alcohols. Finally, we highlight the current challenges and future opportunities within this attractive field.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Coordination Chemistry Reviews

ISSN

0010-8545

e-ISSN

1873-3840

Svazek periodika

541

Číslo periodika v rámci svazku

October

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

32

Strana od-do

nestránkováno

Kód UT WoS článku

001500371100001

EID výsledku v databázi Scopus

2-s2.0-105005950695