Unveiling the Microbial Symphony: Next-Gen Sequencing and Bioinformatics Insights into the Human Gut Microbiome

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43110%2F24%3A43924980" target="_blank" >RIV/62156489:43110/24:43924980 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/24:43924980

Výsledek na webu

<a href="https://doi.org/10.1016/j.hsr.2024.100173" target="_blank" >https://doi.org/10.1016/j.hsr.2024.100173</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.hsr.2024.100173" target="_blank" >10.1016/j.hsr.2024.100173</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Unveiling the Microbial Symphony: Next-Gen Sequencing and Bioinformatics Insights into the Human Gut Microbiome

Popis výsledku v původním jazyce

Hundreds of bacteria, viruses, eukaryotes, and archaea comprise the human intestinal microbiota, which constitutes a complex ecology. Recent years have established the significance of the gastrointestinal microbiome in the study of biological microorganisms. Diverse techniques for cultural extraction and analysis make it difficult to cultivate intestinal gut bacteria species. To determine the causative microorganism, it is necessary to investigate microbes and bacteria. Novel and efficacious remedies for illnesses are required. Bioinformatics and next-generation sequencing can assist in the analysis of enormous quantities of sequenced data for bacterial investigations, thereby expanding sequencing. However, advancements in sequencing technology have broadened the scope of bioinformatics identification and analysis. With next-generation sequencing techniques such as metagenomic, 16S rRNA, and meta-transcriptomic sequencing, experimental data regarding the immunological response of the intestinal gut microbiome to genetic manipulation seems to be helpful in identifying the diseases. Despite significant progress over the past two decades, there is still a lack of understanding about the ecology of diseases and treatments. The present review highlights how microbial gene sequencing and analysis of sequencing information can help manage human gut issues.

Název v anglickém jazyce

Unveiling the Microbial Symphony: Next-Gen Sequencing and Bioinformatics Insights into the Human Gut Microbiome

Popis výsledku anglicky

Hundreds of bacteria, viruses, eukaryotes, and archaea comprise the human intestinal microbiota, which constitutes a complex ecology. Recent years have established the significance of the gastrointestinal microbiome in the study of biological microorganisms. Diverse techniques for cultural extraction and analysis make it difficult to cultivate intestinal gut bacteria species. To determine the causative microorganism, it is necessary to investigate microbes and bacteria. Novel and efficacious remedies for illnesses are required. Bioinformatics and next-generation sequencing can assist in the analysis of enormous quantities of sequenced data for bacterial investigations, thereby expanding sequencing. However, advancements in sequencing technology have broadened the scope of bioinformatics identification and analysis. With next-generation sequencing techniques such as metagenomic, 16S rRNA, and meta-transcriptomic sequencing, experimental data regarding the immunological response of the intestinal gut microbiome to genetic manipulation seems to be helpful in identifying the diseases. Despite significant progress over the past two decades, there is still a lack of understanding about the ecology of diseases and treatments. The present review highlights how microbial gene sequencing and analysis of sequencing information can help manage human gut issues.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Health Sciences Review

ISSN

2772-6320

e-ISSN

2772-6320

Svazek periodika

11

Číslo periodika v rámci svazku

June

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

100173

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—