Hodnoty metalothioneinu v plazmě dítěte otráveného olovem

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F05%3A00086472" target="_blank" >RIV/62156489:43210/05:00086472 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Plasma metallothionein levels in lead poisoned child.

Popis výsledku v původním jazyce

A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55_mol/l, ast 2.94_kat/l, alt 3.46_kat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace aas (varian). Plasma metallothionein levels were measured by electroanalytical technique--voltametric Brdicka reaction. In time of admission, the blood lead was 648_g/l, and metallothionein 153 _mol/l (normal values below 10_mol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the b-Pb decreased to 360 _g/l, u-Pb increased to 6019_g/24 h, p-metallothionein increased to 276_mol/l. After 5 days of chelation treatment, the b-Pb increased (535_g/l), p-metallothionen decreased (147_mol/l). The source of 6 months lead expos

Název v anglickém jazyce

Plasma metallothionein levels in lead poisoned child.

Popis výsledku anglicky

A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55_mol/l, ast 2.94_kat/l, alt 3.46_kat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace aas (varian). Plasma metallothionein levels were measured by electroanalytical technique--voltametric Brdicka reaction. In time of admission, the blood lead was 648_g/l, and metallothionein 153 _mol/l (normal values below 10_mol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the b-Pb decreased to 360 _g/l, u-Pb increased to 6019_g/24 h, p-metallothionein increased to 276_mol/l. After 5 days of chelation treatment, the b-Pb increased (535_g/l), p-metallothionen decreased (147_mol/l). The source of 6 months lead expos

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

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Projekt

<a href="/cs/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Studium obranných mechanismů rostlin při stresu způsobeném těžkými kovy</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Toxicology Letters

ISSN

0378-4274

e-ISSN

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Svazek periodika

158

Číslo periodika v rámci svazku

Suppl. 1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

2

Strana od-do

"S156"-"S157"

Kód UT WoS článku

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EID výsledku v databázi Scopus

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