Metallothionein based biosensor for determination of heavy metals

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F11%3A00183666" target="_blank" >RIV/62156489:43210/11:00183666 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Metallothionein based biosensor for determination of heavy metals

Popis výsledku v původním jazyce

Occurrence of heavy metals in the environment and their entry into the food chain, with all their negative properties is an ongoing problem. The most important role in solving this problem plays rapid and easy-to-use systems for detection of heavy metalsin environment (Cd, Pb, As, Hg). Metallothionein is an intracellular protein which has been known since 1957, and which has very good affinity for heavy metal ions. In its structure up to seven of divalent metal ions can be bound. We attempted to use this feature for designing of our biosensor. Recently there is a greater demand for biosensors where the detection feature is provided via bacteria, peptides, proteins or nucleic acids. The resulting biosensors are characterized by a high specificity and low detection limits. In addition to these properties (the biosensor can be modified to be applicable in situ) but with similar or almost similar results as laboratory measurements. The main objective of this study is to design a biosensor

Název v anglickém jazyce

Metallothionein based biosensor for determination of heavy metals

Popis výsledku anglicky

Occurrence of heavy metals in the environment and their entry into the food chain, with all their negative properties is an ongoing problem. The most important role in solving this problem plays rapid and easy-to-use systems for detection of heavy metalsin environment (Cd, Pb, As, Hg). Metallothionein is an intracellular protein which has been known since 1957, and which has very good affinity for heavy metal ions. In its structure up to seven of divalent metal ions can be bound. We attempted to use this feature for designing of our biosensor. Recently there is a greater demand for biosensors where the detection feature is provided via bacteria, peptides, proteins or nucleic acids. The resulting biosensors are characterized by a high specificity and low detection limits. In addition to these properties (the biosensor can be modified to be applicable in situ) but with similar or almost similar results as laboratory measurements. The main objective of this study is to design a biosensor

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Interdisciplinary Toxicology

ISSN

1337-6853

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

2

Strana od-do

46-47

Kód UT WoS článku

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EID výsledku v databázi Scopus

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