The use of nanotechnology as modern tools to treat infections caused by multiresistant bacteria strains

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F13%3A43908903" target="_blank" >RIV/62156489:43210/13:43908903 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/13:PU126161

Výsledek na webu

<a href="https://mnet.mendelu.cz/mendelnet2013/mnet_2013_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2013/mnet_2013_full.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The use of nanotechnology as modern tools to treat infections caused by multiresistant bacteria strains

Popis výsledku v původním jazyce

This work focuses on development of antimicrobial complex substances, suitable to cover vascular implants with the secondary use in transplantation surgery. This work also presents a comparison of the effects of used nanomaterials against ordinary substances. The formation of complexes took place between silver nanoparticles, silver ions and the polymer substances ( hyaluronic acid, collagen and chitosan). The ability of complex formation of these substances was studied using electrochemistry and spectrophotometry. Bactericidal effect of these compounds was determined by growth-curve methods and inhibition zones on a bacterial culture Staphylococcus aureus. The viability of eukaryotic cells in straight confrontation with tested substances was observedusing the MTT test. According to the data obtained, the complex of silver nanoparticles with chitosan was evaluated as the best substance to ensure antimicrobial behaviour of vascular implants.

Název v anglickém jazyce

The use of nanotechnology as modern tools to treat infections caused by multiresistant bacteria strains

Popis výsledku anglicky

This work focuses on development of antimicrobial complex substances, suitable to cover vascular implants with the secondary use in transplantation surgery. This work also presents a comparison of the effects of used nanomaterials against ordinary substances. The formation of complexes took place between silver nanoparticles, silver ions and the polymer substances ( hyaluronic acid, collagen and chitosan). The ability of complex formation of these substances was studied using electrochemistry and spectrophotometry. Bactericidal effect of these compounds was determined by growth-curve methods and inhibition zones on a bacterial culture Staphylococcus aureus. The viability of eukaryotic cells in straight confrontation with tested substances was observedusing the MTT test. According to the data obtained, the complex of silver nanoparticles with chitosan was evaluated as the best substance to ensure antimicrobial behaviour of vascular implants.

Druh

D - Stať ve sborníku

CEP obor

CG - Elektrochemie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

MendelNet 2013: Proceedings of International PhD Students Conference

ISBN

978-80-7375-908-7

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

929-933

Název nakladatele

Mendelova univerzita v Brně

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

20. 11. 2013

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000366464800164