Pharmaceutical Electrochemistry: the Electrochemical Oxidation of Paracetamol and Its Voltammetric Sensing in Biological Samples Based on Screen Printed Graphene Electrodes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F15%3A43907698" target="_blank" >RIV/62156489:43210/15:43907698 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.electrochemsci.org/papers/vol10/100907440.pdf" target="_blank" >http://www.electrochemsci.org/papers/vol10/100907440.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Pharmaceutical Electrochemistry: the Electrochemical Oxidation of Paracetamol and Its Voltammetric Sensing in Biological Samples Based on Screen Printed Graphene Electrodes

Popis výsledku v původním jazyce

We present a sensitive, fast and unmodified sensor for the electrochemical detection of paracetamol. The electrochemical behaviours of paracetamol on screen printed graphene electrodes were investigated for the first time by cyclic voltammetry. The results showed that the screen printed graphene electrodes revealed exceptional electrocatalytic activity to paracetamol. The response showed by this sensor was enhanced when it was compared to the bare screen printed electrodes. When Screen Printed GrapheneElectrodes were compared to bare SPE, it was shown that the response with graphene was greater than without. This is due to its unique characteristics physical and chemical, pi-pi interactions and a strong adsorptive capability. In this manuscript, the effect of supporting electrolyte, pH and scan rate were also investigated. The oxidation peak current was linearly proportional to the concentration of paracetamol in the range from 0.1 to 50 mu M with a limit of detection of 20nM based on

Název v anglickém jazyce

Pharmaceutical Electrochemistry: the Electrochemical Oxidation of Paracetamol and Its Voltammetric Sensing in Biological Samples Based on Screen Printed Graphene Electrodes

Popis výsledku anglicky

We present a sensitive, fast and unmodified sensor for the electrochemical detection of paracetamol. The electrochemical behaviours of paracetamol on screen printed graphene electrodes were investigated for the first time by cyclic voltammetry. The results showed that the screen printed graphene electrodes revealed exceptional electrocatalytic activity to paracetamol. The response showed by this sensor was enhanced when it was compared to the bare screen printed electrodes. When Screen Printed GrapheneElectrodes were compared to bare SPE, it was shown that the response with graphene was greater than without. This is due to its unique characteristics physical and chemical, pi-pi interactions and a strong adsorptive capability. In this manuscript, the effect of supporting electrolyte, pH and scan rate were also investigated. The oxidation peak current was linearly proportional to the concentration of paracetamol in the range from 0.1 to 50 mu M with a limit of detection of 20nM based on

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Electrochemical Science

ISSN

1452-3981

e-ISSN

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Svazek periodika

10

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

CS - Srbsko a Černá Hora

Počet stran výsledku

13

Strana od-do

7440-7452

Kód UT WoS článku

000365101700047

EID výsledku v databázi Scopus

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