Nutritional and Methodological Perspectives of Zinc Ions and Complexes - Physiological and Pathological States

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F16%3A43909569" target="_blank" >RIV/62156489:43210/16:43909569 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/16:PU120397

Výsledek na webu

<a href="http://dx.doi.org/10.20964/2016.06.38" target="_blank" >http://dx.doi.org/10.20964/2016.06.38</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.20964/2016.06.38" target="_blank" >10.20964/2016.06.38</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nutritional and Methodological Perspectives of Zinc Ions and Complexes - Physiological and Pathological States

Popis výsledku v původním jazyce

Zinc, an essential element playing crucial roles in numerous physiological, but also pathological processes, is still one of the most studied elements. The main importance of this metal is especially based on the structural role of zinc ions in many proteins including the transcription factors, antioxidant enzymes, and metallothioneins. Due to the role of zinc in many crucial physiological processes, its homeostasis must be intensively controlled. The controlling mechanisms are based especially on the zinc transporters and low-molecular proteins metallothioneins (MT). Zinc deficiency has been related with different state of diseases. Here, we primarily aim our attention to zinc and nutrition reviewing the whole process from intake to determination of this metal. The function of zinc ions in proteins with particular emphasis to oxidative stress is discussed followed by intake mechanisms and the role of zinc ions in both physiological and pathological processes. Finally, we summarized the assays used for detection of zinc in complex biological matrices.

Název v anglickém jazyce

Nutritional and Methodological Perspectives of Zinc Ions and Complexes - Physiological and Pathological States

Popis výsledku anglicky

Zinc, an essential element playing crucial roles in numerous physiological, but also pathological processes, is still one of the most studied elements. The main importance of this metal is especially based on the structural role of zinc ions in many proteins including the transcription factors, antioxidant enzymes, and metallothioneins. Due to the role of zinc in many crucial physiological processes, its homeostasis must be intensively controlled. The controlling mechanisms are based especially on the zinc transporters and low-molecular proteins metallothioneins (MT). Zinc deficiency has been related with different state of diseases. Here, we primarily aim our attention to zinc and nutrition reviewing the whole process from intake to determination of this metal. The function of zinc ions in proteins with particular emphasis to oxidative stress is discussed followed by intake mechanisms and the role of zinc ions in both physiological and pathological processes. Finally, we summarized the assays used for detection of zinc in complex biological matrices.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Electrochemical Science

ISSN

1452-3981

e-ISSN

—

Svazek periodika

11

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CS - Srbsko a Černá Hora

Počet stran výsledku

27

Strana od-do

4470-4496

Kód UT WoS článku

000378559300021

EID výsledku v databázi Scopus

2-s2.0-84974815460