Variation of biochemical parameters of energy and liver metabolism in periparturient goats

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F17%3A43912536" target="_blank" >RIV/62156489:43210/17:43912536 - isvavai.cz</a>

Výsledek na webu

<a href="https://mnet.mendelu.cz/mendelnet2017/mnet_2017_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2017/mnet_2017_full.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Variation of biochemical parameters of energy and liver metabolism in periparturient goats

Popis výsledku v původním jazyce

The goal of the study was monitoring of biochemical parameters of energy metabolism in goats in periparturient period and evaluating their correlation with biochemical parameters of liver function. The study was conducted on 10 pregnant white shorthaired goats. Blood samples were collected before parturition (3, 2 and one week), on the day of parturition (day 0) and after parturition (2nd day and 1st, 2nd, 3rd and 4th week). In the blood samples selected biochemical parameters were analysed (glucose -GLU;triglycerides -TGs; cholesterol -CHOL; non-esterified fatty acids -NEFA; beta-hydroxybutyrate -BHB; total bilirubine -TBIL;aspartate aminotransferase-AST; gamma-glutamyl transferase-GGT). The results show that negative energy balance - NEB (characterized by increasing NEFA and BHB concentration and decreasing of TGs concentrations) developed in the postpartum period. The NEB was accompanied by alteration of liver function parameters (increasing of AST and GGT activity and TBIL concentration). Concentration of CHOL was not significantly changed. On the day of parturition enormous increase of glucose was observed with rapid decrease in following days. The results of correlation analysis determined the significant correlation between liver damage parameters (TBIL, AST, GGT) and the parameters of energy metabolism (TGs, NEFA, BHB) in goat&apos;s blood plasma.

Název v anglickém jazyce

Variation of biochemical parameters of energy and liver metabolism in periparturient goats

Popis výsledku anglicky

The goal of the study was monitoring of biochemical parameters of energy metabolism in goats in periparturient period and evaluating their correlation with biochemical parameters of liver function. The study was conducted on 10 pregnant white shorthaired goats. Blood samples were collected before parturition (3, 2 and one week), on the day of parturition (day 0) and after parturition (2nd day and 1st, 2nd, 3rd and 4th week). In the blood samples selected biochemical parameters were analysed (glucose -GLU;triglycerides -TGs; cholesterol -CHOL; non-esterified fatty acids -NEFA; beta-hydroxybutyrate -BHB; total bilirubine -TBIL;aspartate aminotransferase-AST; gamma-glutamyl transferase-GGT). The results show that negative energy balance - NEB (characterized by increasing NEFA and BHB concentration and decreasing of TGs concentrations) developed in the postpartum period. The NEB was accompanied by alteration of liver function parameters (increasing of AST and GGT activity and TBIL concentration). Concentration of CHOL was not significantly changed. On the day of parturition enormous increase of glucose was observed with rapid decrease in following days. The results of correlation analysis determined the significant correlation between liver damage parameters (TBIL, AST, GGT) and the parameters of energy metabolism (TGs, NEFA, BHB) in goat&apos;s blood plasma.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

MendelNet 2017: Proceedings of International PhD Students Conference

ISBN

978-80-7509-529-9

ISSN

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e-ISSN

neuvedeno

Počet stran výsledku

4

Strana od-do

281-284

Název nakladatele

Mendelova univerzita v Brně

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

8. 11. 2017

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000440194500050