Microsatellite detection for variability study of MHC genes region in camels

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F17%3A43912610" target="_blank" >RIV/62156489:43210/17:43912610 - isvavai.cz</a>

Výsledek na webu

<a href="https://mnet.mendelu.cz/mendelnet2017/mnet_2017_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2017/mnet_2017_full.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Microsatellite detection for variability study of MHC genes region in camels

Popis výsledku v původním jazyce

The major histocompatibility complex (MHC) is a genome region containing genes of immune response and genes causing host and pathogen interactions. MHC class I and II genes encode antigen presenting molecules responsible for detection of antigen peptide on cell surface. This is the reason to the great selection pressure on MHC genes includes both positive and negative selection. High polymorphic repetitive sequences - microsatellites are widely used for variability study of specific genome region. The aim of this study is to detect and test some microsatellites located in MHC region and describe its variability and suitability for future testing and usability for multiplex PCR. The model organism for this study is two-armed camel (Camelus bactrianus) for its MHC variability and specific resistance to diseases. Camel MHC region was already not study for variability of microsatellites.

Název v anglickém jazyce

Microsatellite detection for variability study of MHC genes region in camels

Popis výsledku anglicky

The major histocompatibility complex (MHC) is a genome region containing genes of immune response and genes causing host and pathogen interactions. MHC class I and II genes encode antigen presenting molecules responsible for detection of antigen peptide on cell surface. This is the reason to the great selection pressure on MHC genes includes both positive and negative selection. High polymorphic repetitive sequences - microsatellites are widely used for variability study of specific genome region. The aim of this study is to detect and test some microsatellites located in MHC region and describe its variability and suitability for future testing and usability for multiplex PCR. The model organism for this study is two-armed camel (Camelus bactrianus) for its MHC variability and specific resistance to diseases. Camel MHC region was already not study for variability of microsatellites.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

40201 - Animal and dairy science; (Animal biotechnology to be 4.4)

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

MendelNet 2017: Proceedings of International PhD Students Conference

ISBN

978-80-7509-529-9

ISSN

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e-ISSN

neuvedeno

Počet stran výsledku

4

Strana od-do

752-755

Název nakladatele

Mendelova univerzita v Brně

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

8. 11. 2017

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000440194500135