Elevated concentrations of T-2 toxin cause oxidative stress in the rainbow trout (Oncorhynchus mykiss)
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43911739" target="_blank" >RIV/62156489:43210/18:43911739 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/62157124:16170/18:43876934 RIV/62157124:16270/18:43876934 RIV/62157124:16370/18:43876934
Výsledek na webu
<a href="https://doi.org/10.1111/anu.12613" target="_blank" >https://doi.org/10.1111/anu.12613</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/anu.12613" target="_blank" >10.1111/anu.12613</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Elevated concentrations of T-2 toxin cause oxidative stress in the rainbow trout (Oncorhynchus mykiss)
Popis výsledku v původním jazyce
T-2 toxin is a mycotoxin produced by several Fusarium fungi that can contaminate plant components used in feed for aquaculture. The aim of this 28-day study was to investigate the effect of the T-2 toxin in feed in concentrations 1.0 and 1.8 mg/kg (0.01 mg/kg b.w. and 0.018 mg/kg b.w.) on the oxidative stress markers and on the detoxifying enzymes of the rainbow trout. The results showed that T-2 toxin in both tested concentrations induced oxidative stress and antioxidant defence in the liver of trout manifesting by the increase in activities of enzymes glutathione-S-transferase, glutathione reductase and glutathione peroxidase and the decrease in the catalase activity. The increase in lipid peroxidation was recorded only in the higher concentration of T-2 toxin. Ceruloplasmin activity in the plasma increased at both tested concentrations, and the ferric reducing ability of the plasma increased at the higher toxin concentration. The T-2 toxin in feed caused alteration of the total protein, albumin and triacylglycerols as well as the alkaline phosphatase activity in the plasma. Despite no changes in histological examination were found, the influence of T-2 toxin on scavenger system may result in increased sensitivity to other stress factors.
Název v anglickém jazyce
Elevated concentrations of T-2 toxin cause oxidative stress in the rainbow trout (Oncorhynchus mykiss)
Popis výsledku anglicky
T-2 toxin is a mycotoxin produced by several Fusarium fungi that can contaminate plant components used in feed for aquaculture. The aim of this 28-day study was to investigate the effect of the T-2 toxin in feed in concentrations 1.0 and 1.8 mg/kg (0.01 mg/kg b.w. and 0.018 mg/kg b.w.) on the oxidative stress markers and on the detoxifying enzymes of the rainbow trout. The results showed that T-2 toxin in both tested concentrations induced oxidative stress and antioxidant defence in the liver of trout manifesting by the increase in activities of enzymes glutathione-S-transferase, glutathione reductase and glutathione peroxidase and the decrease in the catalase activity. The increase in lipid peroxidation was recorded only in the higher concentration of T-2 toxin. Ceruloplasmin activity in the plasma increased at both tested concentrations, and the ferric reducing ability of the plasma increased at the higher toxin concentration. The T-2 toxin in feed caused alteration of the total protein, albumin and triacylglycerols as well as the alkaline phosphatase activity in the plasma. Despite no changes in histological examination were found, the influence of T-2 toxin on scavenger system may result in increased sensitivity to other stress factors.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
40103 - Fishery
Návaznosti výsledku
Projekt
<a href="/cs/project/QJ1210013" target="_blank" >QJ1210013: Technologie chovu sladkovodních ryb s využitím recirkulačních systémů dánského typu se zaměřením na metody efektivního řízení prostředí a veterinární péče.</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Aquaculture Nutrition
ISSN
1353-5773
e-ISSN
—
Svazek periodika
24
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
8
Strana od-do
842-849
Kód UT WoS článku
000426838800017
EID výsledku v databázi Scopus
2-s2.0-85028617779