Follicular Dendritic Cells in Mammals - An Overview

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F20%3A43917675" target="_blank" >RIV/62156489:43210/20:43917675 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.jmbfs.org/wp-content/uploads/2020/03/jmbfs_1296_Slama.pdf" target="_blank" >https://www.jmbfs.org/wp-content/uploads/2020/03/jmbfs_1296_Slama.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.15414/jmbfs.2020.9.5.946-948" target="_blank" >10.15414/jmbfs.2020.9.5.946-948</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Follicular Dendritic Cells in Mammals - An Overview

Popis výsledku v původním jazyce

Dendritic cells (DCs) are antigen-presenting cells. They recognize antigens and can present these antigens to naïve T lymphocytes. DCs play an important part in the mechanism of adaptive immunity. Namely, they control and regulate adaptive immune responses. DCs secrete cytokines involved in the removal of pathogenic agents. They represent the boundary between innate and adaptive immunity. We can see these cells in lymph nodes, spleen, mucosa and other parts of a body in mammals. Several kinds of dendritic cells differ in positions, structure and functions. One type of DCs is follicular dendritic cells (FDCs). FDCs are located in lymphoid follicles in mammals. FDCs have the main role in binding and retaining antigens by linking to complexes (mainly complement and immune). After they present these pathogenic agents to the germinal center (GC) of B lymphocytes and initiate the secondary immune response. FDCs as well as other DCs play an important part in effective humoral response towards pathogenic agents. Most studies about FDCs are in human and mice and there is a lack of studies that concentrate on bovine follicular dendritic cells (BFDCs). This review provides a brief overview of FDCs in mammals.

Název v anglickém jazyce

Follicular Dendritic Cells in Mammals - An Overview

Popis výsledku anglicky

Dendritic cells (DCs) are antigen-presenting cells. They recognize antigens and can present these antigens to naïve T lymphocytes. DCs play an important part in the mechanism of adaptive immunity. Namely, they control and regulate adaptive immune responses. DCs secrete cytokines involved in the removal of pathogenic agents. They represent the boundary between innate and adaptive immunity. We can see these cells in lymph nodes, spleen, mucosa and other parts of a body in mammals. Several kinds of dendritic cells differ in positions, structure and functions. One type of DCs is follicular dendritic cells (FDCs). FDCs are located in lymphoid follicles in mammals. FDCs have the main role in binding and retaining antigens by linking to complexes (mainly complement and immune). After they present these pathogenic agents to the germinal center (GC) of B lymphocytes and initiate the secondary immune response. FDCs as well as other DCs play an important part in effective humoral response towards pathogenic agents. Most studies about FDCs are in human and mice and there is a lack of studies that concentrate on bovine follicular dendritic cells (BFDCs). This review provides a brief overview of FDCs in mammals.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

10601 - Cell biology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Microbiology, Biotechnology and Food Sciences

ISSN

1338-5178

e-ISSN

—

Svazek periodika

9

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

3

Strana od-do

946-948

Kód UT WoS článku

000523303500013

EID výsledku v databázi Scopus

2-s2.0-85088117401