Nanomaterials with active targeting as advanced antimicrobials
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F20%3A43917830" target="_blank" >RIV/62156489:43210/20:43917830 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/62157124:16810/20:43878426 RIV/00216305:26620/20:PU136557
Výsledek na webu
<a href="https://doi.org/10.1002/wnan.1636" target="_blank" >https://doi.org/10.1002/wnan.1636</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/wnan.1636" target="_blank" >10.1002/wnan.1636</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Nanomaterials with active targeting as advanced antimicrobials
Popis výsledku v původním jazyce
With a growing health threat of bacterial resistance to antibiotics, the nanomaterials have been extensively studied as an alternative. It is assumed that antimicrobial nanomaterials can affect bacteria by several mechanisms simultaneously and thereby overcome antibiotic resistance. Another promising potential use is employing nanomaterials as nanocarriers for antibiotics in order to overcome bacterial defense mechanisms. The passive targeting of nanomaterials is the often used strategy for bacterial treatment, including intracellular infections of macrophages. Furthermore, the specific targeting enhances the efficacy of antimicrobials and reduces side effects. This review aims to discuss advantages, disadvantages, and challenges of nanomaterials in the context of the targeting strategies for antimicrobials as advanced tools for treatments of bacterial infections. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease.
Název v anglickém jazyce
Nanomaterials with active targeting as advanced antimicrobials
Popis výsledku anglicky
With a growing health threat of bacterial resistance to antibiotics, the nanomaterials have been extensively studied as an alternative. It is assumed that antimicrobial nanomaterials can affect bacteria by several mechanisms simultaneously and thereby overcome antibiotic resistance. Another promising potential use is employing nanomaterials as nanocarriers for antibiotics in order to overcome bacterial defense mechanisms. The passive targeting of nanomaterials is the often used strategy for bacterial treatment, including intracellular infections of macrophages. Furthermore, the specific targeting enhances the efficacy of antimicrobials and reduces side effects. This review aims to discuss advantages, disadvantages, and challenges of nanomaterials in the context of the targeting strategies for antimicrobials as advanced tools for treatments of bacterial infections. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10606 - Microbiology
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2020
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
ISSN
1939-5116
e-ISSN
—
Svazek periodika
12
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
25
Strana od-do
"e1636"
Kód UT WoS článku
000530015500001
EID výsledku v databázi Scopus
2-s2.0-85084225290