A Rare Case of Osteomyelitis of an Ankle Caused by Mycobacterium chelonae

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43310%2F23%3A43922795" target="_blank" >RIV/62156489:43310/23:43922795 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/23:10464400 RIV/00179906:_____/23:10464400

Výsledek na webu

<a href="https://doi.org/10.3390/antibiotics12010097" target="_blank" >https://doi.org/10.3390/antibiotics12010097</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/antibiotics12010097" target="_blank" >10.3390/antibiotics12010097</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A Rare Case of Osteomyelitis of an Ankle Caused by Mycobacterium chelonae

Popis výsledku v původním jazyce

Mycobacterium chelonae, a rapidly growing nontuberculous mycobacterium, is usually described as a causative agent of soft tissue infections (postsurgical, posttraumatic, posttransplantation, postinjection, catheter infection, etc.), but only rarely as a cause of osteomyelitis. The authors describe a case report of a 72-year-old man with osteomyelitis of the talus. Initially, the infection was assessed as a soft tissue infection, without any osteolytic changes on the X-ray. After cultivation with subsequent targeted molecular typing of the rpoB gene, M. chelonae was identified from the affected tissue. The bone involvement was subsequently detected on MRI and confirmed histologically with findings of the granulomatous tissue and acid-fast bacilli. The patient was initially treated intravenously with a combination of tigecycline, amikacin, and moxifloxacin for 4 weeks, after which the oral combination of doxycycline and moxifloxacin continued. Identification of the infecting pathogen using molecular typing thus helped to establish the correct diagnosis and represents a rarely described case of osteomyelitis caused by M. chelonae.

Název v anglickém jazyce

A Rare Case of Osteomyelitis of an Ankle Caused by Mycobacterium chelonae

Popis výsledku anglicky

Mycobacterium chelonae, a rapidly growing nontuberculous mycobacterium, is usually described as a causative agent of soft tissue infections (postsurgical, posttraumatic, posttransplantation, postinjection, catheter infection, etc.), but only rarely as a cause of osteomyelitis. The authors describe a case report of a 72-year-old man with osteomyelitis of the talus. Initially, the infection was assessed as a soft tissue infection, without any osteolytic changes on the X-ray. After cultivation with subsequent targeted molecular typing of the rpoB gene, M. chelonae was identified from the affected tissue. The bone involvement was subsequently detected on MRI and confirmed histologically with findings of the granulomatous tissue and acid-fast bacilli. The patient was initially treated intravenously with a combination of tigecycline, amikacin, and moxifloxacin for 4 weeks, after which the oral combination of doxycycline and moxifloxacin continued. Identification of the infecting pathogen using molecular typing thus helped to establish the correct diagnosis and represents a rarely described case of osteomyelitis caused by M. chelonae.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30302 - Epidemiology

Projekt

<a href="/cs/project/NU20-09-00114" target="_blank" >NU20-09-00114: Netuberkulózní mykobakterie v České Republice: současná rizika a zdokonalená prevence</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Antibiotics

ISSN

2079-6382

e-ISSN

2079-6382

Svazek periodika

12

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

9

Strana od-do

97

Kód UT WoS článku

000916783600001

EID výsledku v databázi Scopus

2-s2.0-85146689751