Determination of the porcine MYF6 gene structure by the direct sequencing

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Determination of the porcine MYF6 gene structure by the direct sequencing

Popis výsledku v původním jazyce

The key events in the development of the first skeletal muscles of the vertebrate embryo are initiated and coordinated by the myogenic regulatory factors (MRFs), MYF5, myogenin (MYF4), MyoD (MYF3) and MYF6 (MRF4, herculin). These factors are members of the MyoD family of the basic helix-loop-helix transcription factors, these control the expression of several muscle-specific genes. Herculin is the most abundant of the four known myogenic molecules in sceletal muscle, it controls the terminal differentiation of myoblasts. The aim of our study was the determination of the porcine MYF6 gene structure by direct sequencing of the PCR product. Length of the sequenced fragment was 379 bp. We detected four polymorphisms in this fragment: C/A in position 128, C/G in position 161, A/G in position 192 a C/T in position 282 of the fragment All these polymorphisms were located in the intron.

Název v anglickém jazyce

Determination of the porcine MYF6 gene structure by the direct sequencing

Popis výsledku anglicky

The key events in the development of the first skeletal muscles of the vertebrate embryo are initiated and coordinated by the myogenic regulatory factors (MRFs), MYF5, myogenin (MYF4), MyoD (MYF3) and MYF6 (MRF4, herculin). These factors are members of the MyoD family of the basic helix-loop-helix transcription factors, these control the expression of several muscle-specific genes. Herculin is the most abundant of the four known myogenic molecules in sceletal muscle, it controls the terminal differentiation of myoblasts. The aim of our study was the determination of the porcine MYF6 gene structure by direct sequencing of the PCR product. Length of the sequenced fragment was 379 bp. We detected four polymorphisms in this fragment: C/A in position 128, C/G in position 161, A/G in position 192 a C/T in position 282 of the fragment All these polymorphisms were located in the intron.

Druh

A - Audiovizuální tvorba

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2002

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

ISBN

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Místo vydání

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Název nakladatele resp. objednatele

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Verze

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Identifikační číslo nosiče

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