Klinický management případu polysaccharide storage myopathy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F07%3A00001588" target="_blank" >RIV/62157124:16170/07:00001588 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Clinical management of polysaccharide storage myopathy

Popis výsledku v původním jazyce

Five years old Quarter Horse mare was presented with a history of repeated attacks of stiffness and dark urine. Onset of clinical signs (back and rear legs stiffness, trembling and sweating) was observed within first 30 minutes of exercise and disappeared within four hours. All attacks were observed during last two years, three of them appeared after a few days of rest without feeding reduction. Clinical and haematological examination did not reveal any abnormality. Biochemical examination revealed mildelevation of AST (1374 IU), CK was within normal limits (285 IU). Plasma concentration of vitamin E and whole blood activity of GSH-Px were within normal limits. Biopsy of medial gluteus muscle and its histological examination were performed (H&E, PAS,amylase-PAS). Amylase-PAS reaction revealed amylase resistant polysaccharide granules in muscle fibres. On the basis of histopathology diagnosis of PSSM was established. Grain was withdrawn and feeding with hay was recommended. Because of

Název v anglickém jazyce

Clinical management of polysaccharide storage myopathy

Popis výsledku anglicky

Five years old Quarter Horse mare was presented with a history of repeated attacks of stiffness and dark urine. Onset of clinical signs (back and rear legs stiffness, trembling and sweating) was observed within first 30 minutes of exercise and disappeared within four hours. All attacks were observed during last two years, three of them appeared after a few days of rest without feeding reduction. Clinical and haematological examination did not reveal any abnormality. Biochemical examination revealed mildelevation of AST (1374 IU), CK was within normal limits (285 IU). Plasma concentration of vitamin E and whole blood activity of GSH-Px were within normal limits. Biopsy of medial gluteus muscle and its histological examination were performed (H&E, PAS,amylase-PAS). Amylase-PAS reaction revealed amylase resistant polysaccharide granules in muscle fibres. On the basis of histopathology diagnosis of PSSM was established. Grain was withdrawn and feeding with hay was recommended. Because of

Druh

M - Uspořádání konference

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Místo konání akce

Amsterdam, Netherlands

Stát konání akce

NL - Nizozemsko

Datum zahájení akce

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Datum ukončení akce

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Celkový počet účastníků

1000

Počet zahraničních účastníků

300

Typ akce podle státní přísl. účastníků

EUR - Evropská akce