Laktoferin u feny : příběh pyometry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F08%3A00001970" target="_blank" >RIV/62157124:16170/08:00001970 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Lactoferrin in the dog: a pyometra story

Popis výsledku v původním jazyce

Lactoferrin is an 80 kDa glycoprotein belonging to the family of non-heme iron-binding monomeric glycoproteins. Lactoferrin affects both proliferation and differentiation of immune cells through its ability to modulate cellular signaling pathways.It wasgenerally accepted that dogs produce very limited amount of lactoferrin (if any). In 2007, the lactoferrin was visualized in dog neutrophils using flow cytometry, simultaneously it was isolated from the neutrophils and its high resembling properties withhuman lactoferrin were demonstrated. Pyometra is a serious disease syndrome affecting mainly older nulliparous bitches in the luteal stage of the sexual cycle and is associated with neutrophilia and impaired some immune functions including activity of lymphocytes. A wide range of factors including lactoferrin has been proposed to explain this inhibition. The aim of this work was to measure lactoferrin concentration in the dog and analyze its possible role in a suppressed lymphocyte acti

Název v anglickém jazyce

Lactoferrin in the dog: a pyometra story

Popis výsledku anglicky

Lactoferrin is an 80 kDa glycoprotein belonging to the family of non-heme iron-binding monomeric glycoproteins. Lactoferrin affects both proliferation and differentiation of immune cells through its ability to modulate cellular signaling pathways.It wasgenerally accepted that dogs produce very limited amount of lactoferrin (if any). In 2007, the lactoferrin was visualized in dog neutrophils using flow cytometry, simultaneously it was isolated from the neutrophils and its high resembling properties withhuman lactoferrin were demonstrated. Pyometra is a serious disease syndrome affecting mainly older nulliparous bitches in the luteal stage of the sexual cycle and is associated with neutrophilia and impaired some immune functions including activity of lymphocytes. A wide range of factors including lactoferrin has been proposed to explain this inhibition. The aim of this work was to measure lactoferrin concentration in the dog and analyze its possible role in a suppressed lymphocyte acti

Druh

M - Uspořádání konference

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Místo konání akce

Vienna

Stát konání akce

AT - Rakouská republika

Datum zahájení akce

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Datum ukončení akce

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Celkový počet účastníků

450

Počet zahraničních účastníků

450

Typ akce podle státní přísl. účastníků

EUR - Evropská akce