Healing dynamics of porcine pancreatic parenchyma after radiofrequency ablation - in vivo experimental pilot study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F12%3A43871419" target="_blank" >RIV/62157124:16170/12:43871419 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16810/12:43871699 RIV/65269705:_____/12:#0002223 RIV/00216224:14110/12:00065614

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Healing dynamics of porcine pancreatic parenchyma after radiofrequency ablation - in vivo experimental pilot study

Popis výsledku v původním jazyce

Radiofrequency ablation is a tumor destruction method, widely used in human, even veterinary medicine. Recently, it has been applied to pancreatic disorder treatment. However, little is known about the healing of pancreatic parenchyma after RFA as it isimportant for the prevention of complications and treatment strategy. The aim of this experimental in vivo study on pigs was to evaluate pancreatic parenchyma healing dynamics after being damaged by RFA. RFAs of the duodenal lobe of the pancreas were performed on 8 laboratory pigs. These were euthanized in pairs seven, fourteen, forty and eighty days after the procedure. Histological and cytological changes of the ablated zone were evaluated after an autopsy. It was proved, that pancreatic necrosis after radiofrequency ablation heals by means of fibrotic scar. There was no sign of exocrine and endocrine regeneration respectively during 80 days, after the procedure. This is the first study verifying that the healing process of ablation z

Název v anglickém jazyce

Healing dynamics of porcine pancreatic parenchyma after radiofrequency ablation - in vivo experimental pilot study

Popis výsledku anglicky

Radiofrequency ablation is a tumor destruction method, widely used in human, even veterinary medicine. Recently, it has been applied to pancreatic disorder treatment. However, little is known about the healing of pancreatic parenchyma after RFA as it isimportant for the prevention of complications and treatment strategy. The aim of this experimental in vivo study on pigs was to evaluate pancreatic parenchyma healing dynamics after being damaged by RFA. RFAs of the duodenal lobe of the pancreas were performed on 8 laboratory pigs. These were euthanized in pairs seven, fourteen, forty and eighty days after the procedure. Histological and cytological changes of the ablated zone were evaluated after an autopsy. It was proved, that pancreatic necrosis after radiofrequency ablation heals by means of fibrotic scar. There was no sign of exocrine and endocrine regeneration respectively during 80 days, after the procedure. This is the first study verifying that the healing process of ablation z

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

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Svazek periodika

81

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

427-431

Kód UT WoS článku

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EID výsledku v databázi Scopus

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