The effect of deslorelin acetate on the oestrous cycle The effect of deslorelin acetate on the oestrous cycle of female guinea pigs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F15%3A43873371" target="_blank" >RIV/62157124:16170/15:43873371 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.agriculturejournals.cz/web/vetmed.htm?volume=60&firstPage=155&type=publishedArticle" target="_blank" >http://www.agriculturejournals.cz/web/vetmed.htm?volume=60&firstPage=155&type=publishedArticle</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17221/8062-VETMED" target="_blank" >10.17221/8062-VETMED</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The effect of deslorelin acetate on the oestrous cycle The effect of deslorelin acetate on the oestrous cycle of female guinea pigs

Popis výsledku v původním jazyce

Deslorelin acetate, a GnRH agonist, is commonly used to prevent folliculogenesis in several species. However, little is known of the effect of deslorelin acetate implants on the oestrous cycle of female guinea pigs. Fifteen intact healthy female guinea pigs were investigated in this study. Signs of sexual behaviour, the presence of a vaginal membrane along with plasma concentrations of oestradiol (E2) and progesterone (P4), were monitored during two consecutive oestrous cycles. At the beginning of the third oestrous cycle each guinea pig was administered an implant of the GnRH analogue, deslorelin acetate, (4.7 mg). When compared to the untreated state, deslorelin implantation was associated with altered signs of oestrus. The average time to opening ofthe vaginal membrane was delayed. After opening, the vaginas were found to be variably opened and closed. A significant reduction in P4 (to less than 1.0 ng/ml) and cessation of P4 cyclical variation was observed. Plasma E2 remained high

Název v anglickém jazyce

The effect of deslorelin acetate on the oestrous cycle The effect of deslorelin acetate on the oestrous cycle of female guinea pigs

Popis výsledku anglicky

Deslorelin acetate, a GnRH agonist, is commonly used to prevent folliculogenesis in several species. However, little is known of the effect of deslorelin acetate implants on the oestrous cycle of female guinea pigs. Fifteen intact healthy female guinea pigs were investigated in this study. Signs of sexual behaviour, the presence of a vaginal membrane along with plasma concentrations of oestradiol (E2) and progesterone (P4), were monitored during two consecutive oestrous cycles. At the beginning of the third oestrous cycle each guinea pig was administered an implant of the GnRH analogue, deslorelin acetate, (4.7 mg). When compared to the untreated state, deslorelin implantation was associated with altered signs of oestrus. The average time to opening ofthe vaginal membrane was delayed. After opening, the vaginas were found to be variably opened and closed. A significant reduction in P4 (to less than 1.0 ng/ml) and cessation of P4 cyclical variation was observed. Plasma E2 remained high

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinární medicína

ISSN

0375-8427

e-ISSN

—

Svazek periodika

60

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

155-160

Kód UT WoS článku

000352558900005

EID výsledku v databázi Scopus

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