Biochemical, haematological and oxidative stress responses of common carp (Cyprinus carpio L.) after sub-chronic exposure to copper

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F16%3A43874358" target="_blank" >RIV/62157124:16170/16:43874358 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/16:43910801 RIV/62157124:16270/16:43874358 RIV/62157124:16370/16:43874358

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Biochemical, haematological and oxidative stress responses of common carp (Cyprinus carpio L.) after sub-chronic exposure to copper

Popis výsledku v původním jazyce

The aim of the present study was to investigate the impact of copper-based pesticides (at concentrations of copper of 20, 30, 40 and 70 mu g/l) on one-year-old common carp (Cyprinus carpio L.) during 28 days of exposure. Abnormal behaviour was observed in fish exposed to 70 mu g/l from Day 14. Histological alterations were noticed only in liver in the groups exposed to 40 and 70 mu g/l. Significant changes (P < 0.05) in almost all haematological indices were found, especially in the group exposed to the highest concentration of copper (70 mu g/l). Biochemical analysis revealed various significant (P < 0.05) differences among the tested groups. Significant differences in copper tissue concentration (P < 0.05) among groups were found in liver, gills and kidney. Among antioxidative enzymes, significant changes were revealed mainly in catalase and glutathione-S-transferase activity (P < 0.05). In gills, metallothionein content increased significantly (P < 0.05) in the group exposed to the highest copper concentration (70 mu g/l) compared with the other tested groups, including the control. A significant (P < 0.05) change in total glutathione content was recorded in liver and gills, although the reduced/oxidised ratio was not affected. Oxidative damage to lipids increased significantly (P < 0.05) with increasing copper concentration in liver and kidney. The results demonstrate the deleterious influence of copper on common carp even at low, environmentally relevant concentrations.

Název v anglickém jazyce

Biochemical, haematological and oxidative stress responses of common carp (Cyprinus carpio L.) after sub-chronic exposure to copper

Popis výsledku anglicky

The aim of the present study was to investigate the impact of copper-based pesticides (at concentrations of copper of 20, 30, 40 and 70 mu g/l) on one-year-old common carp (Cyprinus carpio L.) during 28 days of exposure. Abnormal behaviour was observed in fish exposed to 70 mu g/l from Day 14. Histological alterations were noticed only in liver in the groups exposed to 40 and 70 mu g/l. Significant changes (P < 0.05) in almost all haematological indices were found, especially in the group exposed to the highest concentration of copper (70 mu g/l). Biochemical analysis revealed various significant (P < 0.05) differences among the tested groups. Significant differences in copper tissue concentration (P < 0.05) among groups were found in liver, gills and kidney. Among antioxidative enzymes, significant changes were revealed mainly in catalase and glutathione-S-transferase activity (P < 0.05). In gills, metallothionein content increased significantly (P < 0.05) in the group exposed to the highest copper concentration (70 mu g/l) compared with the other tested groups, including the control. A significant (P < 0.05) change in total glutathione content was recorded in liver and gills, although the reduced/oxidised ratio was not affected. Oxidative damage to lipids increased significantly (P < 0.05) with increasing copper concentration in liver and kidney. The results demonstrate the deleterious influence of copper on common carp even at low, environmentally relevant concentrations.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinární medicína

ISSN

0375-8427

e-ISSN

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Svazek periodika

61

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

16

Strana od-do

35-50

Kód UT WoS článku

000376026700006

EID výsledku v databázi Scopus

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