Impact of parasite infections on the gastrointestinal microbiota of free-ranging western lowland gorillas

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Impact of parasite infections on the gastrointestinal microbiota of free-ranging western lowland gorillas

Popis výsledku v původním jazyce

The impact of parasite infections on mammalian gastrointestinal microbiota (GIM) is widely discussed topic. The relationships between pathogenic microorganisms and commensal bacteria are crucial for good development and functioning of gut immune system. Resident GIM products may strongly interfere with the survival and the physiology of many parasites and, consequently, with the outcome of many parasitic infections. However, gastrointestinal parasites (GIP), both protozoans and helminthes, constantly excrete and secrete molecules that may change the environment determining alternations in GIM composition. These changes can be either beneficial or harmful for the host. Here, as for the first time, we investigate the effect of GIP infection on GIM composition in two habituated and two unhabituated groups of wild western lowland gorillas (Gorilla g. gorilla) from the Dzanga Sangha Protected Areas, Central African Republic. We coproscopically examined 64 fecal samples for GIP and determined the levels of strongylid nematodes. We characterized GIM composition through 454 pyrosequencing of the bacterial 16S rRNA gene. The comparison of GIM profiles of individuals from four different groups indicated that the relative abundance of specific bacterial taxa significantly differ as well as the intensity of strongylid infections among groups. However, our results suggest that differences in GIM composition of studied groups are not induced by GIP infections. Other factors shaping the GIM will be discussed.

Název v anglickém jazyce

Impact of parasite infections on the gastrointestinal microbiota of free-ranging western lowland gorillas

Popis výsledku anglicky

The impact of parasite infections on mammalian gastrointestinal microbiota (GIM) is widely discussed topic. The relationships between pathogenic microorganisms and commensal bacteria are crucial for good development and functioning of gut immune system. Resident GIM products may strongly interfere with the survival and the physiology of many parasites and, consequently, with the outcome of many parasitic infections. However, gastrointestinal parasites (GIP), both protozoans and helminthes, constantly excrete and secrete molecules that may change the environment determining alternations in GIM composition. These changes can be either beneficial or harmful for the host. Here, as for the first time, we investigate the effect of GIP infection on GIM composition in two habituated and two unhabituated groups of wild western lowland gorillas (Gorilla g. gorilla) from the Dzanga Sangha Protected Areas, Central African Republic. We coproscopically examined 64 fecal samples for GIP and determined the levels of strongylid nematodes. We characterized GIM composition through 454 pyrosequencing of the bacterial 16S rRNA gene. The comparison of GIM profiles of individuals from four different groups indicated that the relative abundance of specific bacterial taxa significantly differ as well as the intensity of strongylid infections among groups. However, our results suggest that differences in GIM composition of studied groups are not induced by GIP infections. Other factors shaping the GIM will be discussed.

Druh

O - Ostatní výsledky

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů