Schistosoma mansoni in western lowland gorillas and chimpanzees in Loango National Park, Gabon

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F17%3A43875503" target="_blank" >RIV/62157124:16170/17:43875503 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Schistosoma mansoni in western lowland gorillas and chimpanzees in Loango National Park, Gabon

Popis výsledku v původním jazyce

Schistosomiasis is a widespread zoonosis in sub-Saharan Africa and can have severe socioeconomic and public health impact. Most of the human schistosome species can produce patent infection in other mammals including nonhuman primates, hosts that can in turn serve as reservoirs of the infection. Almost all information we have comes from experimental condition which confirmed that the course and morbidity of S. mansoni infection in chimpanzees strongly resembles that reported for humans, including severe liver fibrosis and may lead to death. We detected eggs of Schistosoma mansoni in western lowland gorilla and central chimpanzee fecal samples in Loango National Park, Gabon. We analyzed internal transcribed spacer (ITS) and cytochrome c oxidase subunit 1 (cox 1) fragments using maximum likelihood phylogenetic analyses and haplotype network respectively and showed the position of our samples from gorillas and chimpanzees within the S. mansoni clade. This is the first record of any schistosome species in gorilla and first confirmed record of S. mansoni in Gabon which urges surveillance in the area and prompts questions regarding the extent of zoonotic transmission and the clinical impact.

Název v anglickém jazyce

Schistosoma mansoni in western lowland gorillas and chimpanzees in Loango National Park, Gabon

Popis výsledku anglicky

Schistosomiasis is a widespread zoonosis in sub-Saharan Africa and can have severe socioeconomic and public health impact. Most of the human schistosome species can produce patent infection in other mammals including nonhuman primates, hosts that can in turn serve as reservoirs of the infection. Almost all information we have comes from experimental condition which confirmed that the course and morbidity of S. mansoni infection in chimpanzees strongly resembles that reported for humans, including severe liver fibrosis and may lead to death. We detected eggs of Schistosoma mansoni in western lowland gorilla and central chimpanzee fecal samples in Loango National Park, Gabon. We analyzed internal transcribed spacer (ITS) and cytochrome c oxidase subunit 1 (cox 1) fragments using maximum likelihood phylogenetic analyses and haplotype network respectively and showed the position of our samples from gorillas and chimpanzees within the S. mansoni clade. This is the first record of any schistosome species in gorilla and first confirmed record of S. mansoni in Gabon which urges surveillance in the area and prompts questions regarding the extent of zoonotic transmission and the clinical impact.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/GA15-05180S" target="_blank" >GA15-05180S: Genetická diverzita a přenosy strongylidních hlístic mezi africkými lidoopy a lidmi</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů