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Cranial cruciate ligament structure in relation to the tibial plateau slope and intercondylar notch width in dogs

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F18%3A43876299" target="_blank" >RIV/62157124:16170/18:43876299 - isvavai.cz</a>

  • Výsledek na webu

    <a href="https://synapse.koreamed.org/DOIx.php?id=10.4142/jvs.2018.19.5.699" target="_blank" >https://synapse.koreamed.org/DOIx.php?id=10.4142/jvs.2018.19.5.699</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4142/jvs.2018.19.5.699" target="_blank" >10.4142/jvs.2018.19.5.699</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Cranial cruciate ligament structure in relation to the tibial plateau slope and intercondylar notch width in dogs

  • Popis výsledku v původním jazyce

    Cranial cruciate ligament (CCL) rupture is one of the most common orthopedic conditions in dogs. The pathogenesis of CCL rupture is not fully described and remains to be elucidated fully. Several hypotheses have been proposed to explain the etiology of these changes. The objective of this study was to investigate structural changes in the CCL in relation to the tibial plateau angle (TPA) and the intercondylar notch (ICN) width in dogs. Fifty-five skeletally mature dogs were included in this study. ICN width and TPA measurements were obtained from intact CCL stifles. Samples of the CCL, caudal cruciate ligament (CaCL), and femoral head ligament (FHL) were harvested and stained for routine histological and immunohistochemical analysis. Microscopic changes in the ligaments were observed and were found to correlate with the TPA and ICN width values. The degree of structural changes within the CCL was observed to correlate with an increasing TPA and a narrowing ICN width. Changes in the CCL are likely to be caused by excessive forces acting through the ligament in stifles with a high TPA. Chondroid metaplasia of the CCL is an adaptation to abnormal mechanics within the stifle joint caused by altered bone morphology.

  • Název v anglickém jazyce

    Cranial cruciate ligament structure in relation to the tibial plateau slope and intercondylar notch width in dogs

  • Popis výsledku anglicky

    Cranial cruciate ligament (CCL) rupture is one of the most common orthopedic conditions in dogs. The pathogenesis of CCL rupture is not fully described and remains to be elucidated fully. Several hypotheses have been proposed to explain the etiology of these changes. The objective of this study was to investigate structural changes in the CCL in relation to the tibial plateau angle (TPA) and the intercondylar notch (ICN) width in dogs. Fifty-five skeletally mature dogs were included in this study. ICN width and TPA measurements were obtained from intact CCL stifles. Samples of the CCL, caudal cruciate ligament (CaCL), and femoral head ligament (FHL) were harvested and stained for routine histological and immunohistochemical analysis. Microscopic changes in the ligaments were observed and were found to correlate with the TPA and ICN width values. The degree of structural changes within the CCL was observed to correlate with an increasing TPA and a narrowing ICN width. Changes in the CCL are likely to be caused by excessive forces acting through the ligament in stifles with a high TPA. Chondroid metaplasia of the CCL is an adaptation to abnormal mechanics within the stifle joint caused by altered bone morphology.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    40301 - Veterinary science

Návaznosti výsledku

  • Projekt

  • Návaznosti

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2018

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    Journal of veterinary science

  • ISSN

    1229-845X

  • e-ISSN

  • Svazek periodika

    19

  • Číslo periodika v rámci svazku

    5

  • Stát vydavatele periodika

    KR - Korejská republika

  • Počet stran výsledku

    9

  • Strana od-do

    699-707

  • Kód UT WoS článku

    000445944700015

  • EID výsledku v databázi Scopus

    2-s2.0-85054733098